Results 231 to 240 of about 73,620 (322)

Comparison of severe aplastic anaemia and lower risk hypoplastic myelodysplastic neoplasms: Critical role of megakaryocyte count in distinguishing aplastic anaemia from myelodysplastic neoplasms

British Journal of Haematology, EarlyView.
In our central morphological review system, megakaryocyte counts are prioritized alongside BM cellularity to differentiate between AA and MDS. A retrospective analysis of patients with SAA and those with LR‐hMDS, registered in that system, revealed a significant difference in outcomes.
Tomoya Maeda, Akira Matsuda, Junya Kanda, Hiroshi Kawabata, Takayuki Ishikawa, Kaoru Tohyama, Akira Kitanaka, Kayano Araseki, Kei Shimbo, Tomoko Hata, Takahiro Suzuki, Hidekazu Kayano, Kensuke Usuki, Maki Shindo‐Ueda, Nobuyoshi Arima, Masaharu Nohgawa, Akiko Ohta, Shigeru Chiba, Yasushi Miyazaki, Shinji Nakao, Keiya Ozawa, Shunya Arai, Mineo Kurokawa, Akifumi Takaori‐Kondo, Kinuko Mitani, the Japanese National Research Group on Idiopathic Bone Marrow Failure Syndromes   +25 more
wiley   +1 more source

Chromosomes of four species of dobsonflies, in the genus <i>Protohermes</i> (Megaloptera, Corydalidae, Corydalinae) from East Asia. [PDF]

Comp Cytogenet
Takeuchi Y, Iizuka K, Koishi H, Hoshiba H.   +3 more
europepmc   +1 more source

Multiple myeloma with 1q gain/amplification exhibits reduced CD38 expression via interleukin‐6 receptor overexpression

British Journal of Haematology, EarlyView.
Multiple myeloma (MM) with chromosome 1q21 gain/amplification (1q+) has been reported to respond poorly to daratumumab, a human monoclonal antibody targeting CD38. Our findings revealed significantly lower CD38 expression in patients with 1q+ MM than in those with 1q wild type (WT) MM.
Wataru Kuroki, Akihiro Kitadate, Yuto Takahashi, Sayaka Iwama, Masahiro Yamada, Takahiro Kobayashi, Sho Ikeda, Kentaro Narita, Kosei Matsue, Naoto Takahashi   +9 more
wiley   +1 more source

Editorial: MDS: new scientific and clinical developments. [PDF]

Front Oncol
Blum S, Symeonidis A, Germing U.
europepmc   +1 more source

STAB1 Promotes Acute Myeloid Leukemia Progression by Activating the IKK/NF‐κB Pathway and Increasing M2 Macrophage Polarization

Cancer Science, EarlyView.
In this study, we explored the effects of silenced STAB1 expression in AML cells on the polarization of M2‐like macrophages, as well as the involvement of nuclear factor‐kappa B (NF‐κB) signaling pathways in the pro‐oncogenic roles of STAB1. By investigating the expression pattern of STAB1 along with its regulatory mechanisms in AML patients, we aimed ...
Jiaxiu Yin, Jing Luo, Lan Wang, Lanxiang Liu, Lin Liu   +4 more
wiley   +1 more source

P592: Cytogenetic and microarray analysis of prenatally detected congenital heart defects (CHD): Diagnostic findings and variation among CHD subtypes

Genetics in Medicine Open
Stuart Schwartz, Alexandra Arreola, Inder Gadi, Gloria Haskell, Bing Huang, Judith Knops, Andrea Penton, Karen Phillips   +7 more
doaj  

Case Report - Severe hypospadias in 46, XY karyotype patients: is third level genetic testing always mandatory? [PDF]

Front Surg
Romano G, Rollo G, Spagnol L, Mucciolo M, Adorisio O, Silveri M.   +5 more
europepmc   +1 more source

Pimitespib, an HSP90 Inhibitor, Enhances the Efficacy of PARP Inhibitors in PARP Inhibitor‐Insensitive Breast Cancer Cells

Cancer Science, EarlyView.
Pimitespib, an HSP90 inhibitor, enhances the antitumor activity of PARP inhibitors by impairing the homologous recombination (HR) repair pathway in PARP inhibitor‐insensitive breast cancer cells. This is achieved by promoting the downregulation of proteins involved in HR, such as BRCA1, BRCA2, and RAD51.
Hiromi Muraoka, Hiromi Kazuno, Akihiro Hashimoto, Hiroshi Sootome, Shuichi Ohkubo   +4 more
wiley   +1 more source

Extramedullary Relapse of Acute Promyelocytic Leukaemia (APL) at an Unusual Site (External Auditory Canal). [PDF]

EJHaem
Iyer P, Hudson C, Sohail K, Mihailescu L, Bolam S.   +4 more
europepmc   +1 more source

Cytogenetic Studies in Lower Vertebrates. I

, 1966
Yoshio Ojima, S. Hitotsumachi, Sajiro Makino   +2 more
openalex   +2 more sources