Establishment and Characterization of MCA23, a Novel Mouse Intrahepatic Cholangiocarcinoma Cell Line
ABSTRACT Introduction Intrahepatic cholangiocarcinoma (ICC) is an aggressive type of malignancy. Recent advancements have highlighted the importance of the tumor immune microenvironment in therapeutic responses and prognosis. However, the lack of a mouse‐derived ICC cell line and current mouse models limit explorations of the TME in ICC.
Yuchao He +12 more
wiley +1 more source
Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia Patients Have Dismal Outcomes Irrespective of Allogeneic Hematopoietic Stem Cell Transplant: A Single-Center Experience. [PDF]
Llaurador G +8 more
europepmc +1 more source
Digenic Functional B12 and Folate Defect Mimicking Myelodysplasia
Proposed mechanistic model of mutation‐related outcomes. ABSTRACT A digenic defect involving CUBN and MTHFR produced functional B12/folate deficiency in a patient with pancytopenia and neurological signs, mimicking myelodysplasia. Genetic and metabolic screening revealed elevated methylmalonic acid/homocysteine, with rapid remission post‐parenteral B12.
Thomas Cluzeau +3 more
wiley +1 more source
P140: A rare phenomenon: Double trisomy rescue detected during clinical SNP microarray testing*
Andrea Penton +4 more
doaj +1 more source
Impact of daratumumab refractoriness on clinical outcomes following CAR T-cell therapy for relapsed refractory multiple myeloma. [PDF]
Sebastian T +22 more
europepmc +1 more source
Generation of alphoid DNA probes for fluorescence in situ hybridization using the polymerase chain reaction [PDF]
Cremer, Thomas +3 more
core
Situs Inversus Totalis: A Case Report and Literature Review
ABSTRACT Situs Inversus Totalis (SIT) is a rare congenital anomaly characterized by the complete mirror‐image transposition of the thoracoabdominal viscera. Although typically it has a favorable prognosis, SIT can be associated with ciliopathy‐related disorders, most notably Primary Ciliary Dyskinesia (PCD).
Xin Du +4 more
wiley +1 more source
Cytogenomics and optical genome mapping approaches characterize a derivative interstitial monosomy 18p due to a maternal complex intrachromosomal rearrangement. [PDF]
Graziani L +11 more
europepmc +1 more source
Prognostic significance of cytogenetic risk score in patients with secondary acute myeloid leukemia undergoing allogeneic stem cell transplantation from HLA-matched unrelated donors: a study from the ALWP /EBMT. [PDF]
Nagler A +17 more
europepmc +1 more source

