Results 21 to 30 of about 78,018 (293)
Impact of cytogenetics on outcomes in pediatric acute lymphoblastic leukemia
South Asian Journal of Cancer, 2018 Context: In acute lymphoblastic leukemia (ALL), the most important prognostic factors are age, leukocyte count at presentation, immunophenotype, and cytogenetic abnormalities.
Rachana Chennamaneni +5 more
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PLoS ONE, 2016 BackgroundAlthough cytogenetics-based prognostication systems are well described in acute myeloid leukemia (AML), overall survival (OS) remains highly variable within risk groups.
Caroline E Sloan +10 more
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PLoS ONE, 2018 We analyzed treatment outcomes and prognostic factors in adult patients with therapy-related myeloid neoplasms (t-MNs) to select patients who would be benefited by active anticancer treatment. After excluding 18 patients who received palliative care only
Sang-A Kim +7 more
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Molecular Cytogenetics in the Era of Chromosomics and Cytogenomic Approaches
Frontiers in Genetics, 2021 Here the role of molecular cytogenetics in the context of yet available all other cytogenomic approaches is discussed. A short introduction how cytogenetics and molecular cytogenetics were established is followed by technical aspects of fluorescence in ...
Thomas Liehr
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Comprehensive analysis of genetic factors predicting overall survival in Myelodysplastic syndromes
Scientific Reports, 2022 Myelodysplastic syndromes (MDS) are a group of clonal hematological disease with high risk of progression to AML. Accurate risk stratification is of importance for the proper management of MDS.
Nehakumari Maurya +8 more
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The Prognostic Role of Cytogenetics Analysis in Philadelphia Negative Myeloproliferative Neoplasms
Medicina, 2021 Myeloproliferative neoplasms (MPNs) are clonal stem cell disorders characterized collectively by clonal proliferation of myeloid cells with variable morphologic maturity and hematopoietic efficiency. Although the natural history of these neoplasms can be
Giuseppe Lanzarone, Matteo Olivi
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Human molecular cytogenetics: from cells to nucleotides
Genetics and Molecular Biology, 2014 The field of cytogenetics has focused on studying the number, structure, function and origin of chromosomal abnormalities and the evolution of chromosomes. The development of fluorescent molecules that either directly or via an intermediate molecule bind
Mariluce Riegel
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Chromosomal abnormalities in 163 Tunisian couples with recurrent miscarriages
The Pan African Medical Journal, 2017 Recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses before 24 weeks of gestation. Parental chromosomal abnormalities represent an important etiology of RM.
Wiem Ayed +8 more
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cytogenetic findings at Down syndrome and their correlation with clinical findings
Biomolecules & Biomedicine, 2005 Down syndrome is a genetic state characterized by trisomy of chromosome 21. In the retrospective study for 12 years period (1991-2002) we have conducted correlation between cytogenetics analyses and clinical findings in our centre at 96 male and 83 ...
Amra Ćatović, Sulejman Kendić
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