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Cytogenetics of lymphomas [PDF]
Cytogenetic analysis is now a routine part of the diagnosis and management of a significant number of lymphoid malignancies. Whilst conventional cytogenetics remains the most comprehensive method for assessing chromosome abnormalities, the technical difficulties associated with conventional cytogenetics in most lymphomas has resulted in increased use ...
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Current Biology, 1992
Chromosome variants are well established as useful genetic markers and integral components both of the genetic structure of populations, and in speciation. The current explosion of molecular techniques is facilitating the localization of many DNA sequences, while a reassessment of the fitness of chromosome mutants challenges some classical views on ...
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Chromosome variants are well established as useful genetic markers and integral components both of the genetic structure of populations, and in speciation. The current explosion of molecular techniques is facilitating the localization of many DNA sequences, while a reassessment of the fitness of chromosome mutants challenges some classical views on ...
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Annual Review of Genetics, 1975
The mouse has a number of favorable attributes for genetic studies. It is a mammal, and its many biochemical and physiological similarities to the human make its study particularly relevant to human genetics and medicine. It is easy to handle and breeds relatively quickly so that as many as a hundred consecutive generations can be studied in one human ...
Dorothy A. Miller, Orlando J. Miller
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The mouse has a number of favorable attributes for genetic studies. It is a mammal, and its many biochemical and physiological similarities to the human make its study particularly relevant to human genetics and medicine. It is easy to handle and breeds relatively quickly so that as many as a hundred consecutive generations can be studied in one human ...
Dorothy A. Miller, Orlando J. Miller
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Archives of Internal Medicine, 1960
The direct study of human chromosomes has only recently become of significance in medicine. This has been made possible by several important advances in cytological technique, leading to the unexpected discovery in 1956 by Tjio and Levan 1 that the human chromosome number was 46 and not 48.
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The direct study of human chromosomes has only recently become of significance in medicine. This has been made possible by several important advances in cytological technique, leading to the unexpected discovery in 1956 by Tjio and Levan 1 that the human chromosome number was 46 and not 48.
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New England Journal of Medicine, 1984
For many years it has been recognized that patients who apparently have the same type of leukemia have different prognoses and different responses to treatment.
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For many years it has been recognized that patients who apparently have the same type of leukemia have different prognoses and different responses to treatment.
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Environmental and Molecular Mutagenesis, 1994
A fascination with chromosomes, especially chromosomal aberrations, linked many at the Oak Ridge National Laboratory and the Medical Research Council Radiobiological Research Unit at Harwell, but they disagreed about the correctness of Revell's exchange hypothesis.
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A fascination with chromosomes, especially chromosomal aberrations, linked many at the Oak Ridge National Laboratory and the Medical Research Council Radiobiological Research Unit at Harwell, but they disagreed about the correctness of Revell's exchange hypothesis.
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Archives of Pediatrics & Adolescent Medicine, 1976
In November 1970, approximately 90 cytogeneticists convened at Colorado Springs, Colo, to participate in a conference titled "Perspectives in Cytogenetics."1 The purpose of the conference sponsored by the National Institute of Child Health and Human Development was to review the remarkable advances in cytogenetics of the preceding decade and to peer ...
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In November 1970, approximately 90 cytogeneticists convened at Colorado Springs, Colo, to participate in a conference titled "Perspectives in Cytogenetics."1 The purpose of the conference sponsored by the National Institute of Child Health and Human Development was to review the remarkable advances in cytogenetics of the preceding decade and to peer ...
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Cancer Investigation, 1998
Introduction The study of chromosomes in leukemia has contributed significantly to understanding the biology of the disease, including both some of the molecular (genetic) aberrations involved in pathogenesis and prediction of response to treatment. Cytogenetic aberrations in malignancy can be either primary or secondary (1,2).
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Introduction The study of chromosomes in leukemia has contributed significantly to understanding the biology of the disease, including both some of the molecular (genetic) aberrations involved in pathogenesis and prediction of response to treatment. Cytogenetic aberrations in malignancy can be either primary or secondary (1,2).
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Wiener Medizinische Wochenschrift, 2005
Cytogenetic analysis by classical chromosome banding, in combination with different fluorescence in situ hybridization (FISH) based methods, including comparative genomic hybridization and multicolour FISH, provides important information concerning the diagnosis, staging and prognosis of, as well as the planning of therapeutic intervention against ...
Elisabeth Krömer, Christa Fonatsch
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Cytogenetic analysis by classical chromosome banding, in combination with different fluorescence in situ hybridization (FISH) based methods, including comparative genomic hybridization and multicolour FISH, provides important information concerning the diagnosis, staging and prognosis of, as well as the planning of therapeutic intervention against ...
Elisabeth Krömer, Christa Fonatsch
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American Journal of Obstetrics and Gynecology, 1977
The advantage of a standardized nomenclature is apparent in any discipline. A standardized method for designating carbon molecules in steroid chemistry facilitates communication in endocrinology; consistent staging methods permit comparison of data in oncology.
J L, Simpson, A O, Martin
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The advantage of a standardized nomenclature is apparent in any discipline. A standardized method for designating carbon molecules in steroid chemistry facilitates communication in endocrinology; consistent staging methods permit comparison of data in oncology.
J L, Simpson, A O, Martin
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