Results 31 to 40 of about 232,074 (411)
PLoS ONE, 2018 We analyzed treatment outcomes and prognostic factors in adult patients with therapy-related myeloid neoplasms (t-MNs) to select patients who would be benefited by active anticancer treatment. After excluding 18 patients who received palliative care only
Sang-A Kim +7 more
doaj +1 more source
Molecular Cytogenetics in the Era of Chromosomics and Cytogenomic Approaches
Frontiers in Genetics, 2021 Here the role of molecular cytogenetics in the context of yet available all other cytogenomic approaches is discussed. A short introduction how cytogenetics and molecular cytogenetics were established is followed by technical aspects of fluorescence in ...
Thomas Liehr
doaj +1 more source
Comprehensive analysis of genetic factors predicting overall survival in Myelodysplastic syndromes
Scientific Reports, 2022 Myelodysplastic syndromes (MDS) are a group of clonal hematological disease with high risk of progression to AML. Accurate risk stratification is of importance for the proper management of MDS.
Nehakumari Maurya +8 more
doaj +1 more source
A Postgenomic Perspective on Molecular Cytogenetics
Current Genomics, 2017 Background: The postgenomic era is featured by massive data collection and analyses from various large scale-omics studies. Despite the promising capability of systems biology and bioinformatics to handle large data sets, data interpretation, especially ...
H. Heng +6 more
semanticscholar +1 more source
Advances in Microfluidics and Lab-on-a-Chip Technologies [PDF]
Molecular Diagnostics (3rd Ed.), Academic Press, 2017, pp 197-217,
ISBN 9780128029718, 2017 Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and nanotechnologies has enabled both new capabilities and instrument sizes practical for point-of-care. It has also introduced
arxiv +1 more source
History and evolution of cytogenetics
Molecular Cytogenetics, 2015 The events that have led to the development of cytogenetics as a specialty within the life sciences are described, with special attention to the early history of human cytogenetics.
M. Ferguson-Smith
semanticscholar +1 more source
Analysis of hybridization in French wild boar populations using genome-wide genotyping data [PDF]
arXiv, 2021 The "genetic purity" of French wild boar populations has been monitored since the 1980s based on a cytogenetic difference between wild boars and domestic pigs (36 and 38 chromosomes, respectively). This difference makes it possible to identify any boar with 37 or 38 chromosomes as "hybrid", without however being able to determine the origin (recent or ...
arxiv
Cytogenetics and molecular cytogenetics in Hodgkin's disease
Annals of Oncology, 1996 For about 20 years we have known from cytogenetic studies that there is a clonal cell population in Hodgkin's disease. Most karyotypes are complexly aberrant and chromosome numbers typically lie in the hyperploid range. Some chromosome regions seem to be preferentially involved, but a chromosome aberration specific for Hodgkin's disease has not yet ...
K. Weber-Matthiesen +2 more
openaire +2 more sources
Chromosomal in situ suppression hybridization of human gonosomes and autosomes and its use in clinical cytogenetics [PDF]
, 1990 DNA libraries from sorted human gonosomes were used selectively to stain the X and Y chromosomes in normal and aberrant cultured human cells by chromosomal in situ suppression (CISS-) hybridization.
Cremer, Thomas +5 more
core +1 more source
An explainable model to support the decision about the therapy protocol for AML [PDF]
, 2023 Acute Myeloid Leukemia (AML) is one of the most aggressive types of hematological neoplasm. To support the specialists' decision about the appropriate therapy, patients with AML receive a prognostic of outcomes according to their cytogenetic and molecular characteristics, often divided into three risk categories: favorable, intermediate, and adverse ...
arxiv +1 more source