Results 151 to 160 of about 1,666,972 (256)

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Cutting edge:Suppressor of cytokine signaling 3 inhibits activation of NFATp

, 2002
Recent studies have suggested that signaling initiated by the activation of Ag receptors and signaling activated through cytokine receptors may be regulated by a common set of inhibitory proteins.
Banerjee, A, Chen, XP, Rothman, PB, Nawijn, MC; id_orcid, Banks, AS, Nawijn, MC (Martijn), Nawijn, MC   +6 more
core   +1 more source

Encoded Cell-Material Interactions to Reroute Cytokine Signaling for Regenerative Medicine. [PDF]

Adv Healthc Mater
Eidman ZM, Sharma J, Lee JC, Schulze NF, Brien HJ, Corn KC, Rafat M, Brunger JM.   +7 more
europepmc   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Omega-3 fatty acids reprogram tumor-associated macrophage cytokine signaling and suppress pancreatic cancer growth. [PDF]

Proc Natl Acad Sci U S A
Sakuma S, Zhao S, Hildreth A, Liu G, Shah V, Sun M, Tan S, Jacobs E, LaPorta MA, Furguiele J, Avina-Ochoa N, Globig AM, Tripple V, ImmgenT Consortium, Maier G, Panda S, Reyzer ML, Kang JX, Ma DWL, Rodeheffer M, Shaikh SR, Kaech SM.   +21 more
europepmc   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu, Peng Guo, Rui Pan, Zhenghao Wang, Jingchao Zhou, Pengcheng Zhang, Xingzhe Zhang, Qinghua Zhang, Haibin Ma, Zhanfeng Niu   +9 more
wiley   +1 more source

Gut-derived Unpaired-3 cytokine signaling promotes systemic hypoxia tolerance in Drosophila. [PDF]

Dis Model Mech
Ding K, Bodkhe P, Lee B, Ingelson-Filpula WA, Polan D, Wycislik A, Cheung T, Wu S, Rahim R, Grewal SS.   +9 more
europepmc   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

Arthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada, Marcos Rafael N. Cavalcante, Itamar de Souza Santos, Márcio S. Bittencourt, Vandrize Meneghini, Paulo A. Lotufo, Alessandra C. Goulart, Isabela M. Bensenor   +7 more
wiley   +1 more source

Differential requirements for cytokine signaling and local antigen in upper versus lower respiratory tract CD8+ TRM development. [PDF]

J Immunol
Rodgers KK, Williams ME, Jimenez AR, Hicks SL, Mattingly CLR, Michalets SE, Soto-Vázquez YM, Moore KM, Rasche MM, Lawrence LA, Huang YS, Chen TD, Cendoya SR, Scharer CD, Swaims-Kohlmeier A, Kohlmeier JE.   +15 more
europepmc   +1 more source