Results 1 to 10 of about 1,114,614 (156)
Cytokines and chemokines: The vital role they play in herpes simplex virus mucosal immunology
Frontiers in Immunology, 2022 Herpes simplex viruses (HSV) types 1 and 2 are ubiquitous infections in humans. They cause orofacial and genital herpes with occasional severe complications. HSV2 also predisposes individuals to infection with HIV.
Anthony Cunningham +2 more
exaly +2 more sources
Cytokines and interventional immunology [PDF]
Nature Reviews Immunology, 2007 Alterations in cytokine expression associated with inflammation have long been observed in individuals with immune-mediated disease. Clinical trials carried out almost a decade ago were the first to show that therapeutic manipulation of cytokines with monoclonal antibodies targeting tumour-necrosis factor could change the course of an autoimmune ...
David Hafler
exaly +2 more sources
The Multifaceted Immunology of Cytokine Storm Syndrome
The Journal of Immunology, 2023 Cytokine storm syndromes (CSS) are potentially fatal hyperinflammatory states that share the underpinnings of persistent immune cell activation and uninhibited cytokine production.
Pui Y. Lee, R. Cron
semanticscholar +3 more sources
International Journal of Molecular Sciences, 2019 The IL-36 subfamily of cytokines has been recently described as part of the IL-1 superfamily. It comprises three pro-inflammatory agonists (IL-36α, IL-36β, and IL-36γ), their receptor (IL-36R), and one antagonist (IL-36Ra).
Sandra Rodríguez +2 more
exaly +2 more sources
IL-12 Family Cytokines: Immunological Playmakers [PDF]
Nature Immunology, 2012 The interleukin 12 (IL-12) family is unique in having the only heterodimeric cytokines, including IL-12, IL-23, IL-27 and IL-35. This feature endows these cytokines with a unique set of connections and functional interactions not shared by other cytokine
D. Vignali, V. Kuchroo
semanticscholar +3 more sources
The effect of cytokines on osteoblasts and osteoclasts in bone remodeling in osteoporosis: a review
Frontiers in Immunology, 2023 The complicated connections and cross talk between the skeletal system and the immune system are attracting more attention, which is developing into the field of Osteoimmunology.
Jie Xu, +4 more
semanticscholar +1 more source
Association of Inflammatory Cytokines With Non-Alcoholic Fatty Liver Disease
Frontiers in Immunology, 2022 Background Inflammatory cytokines have been considered to be significant factors contributing to the development and progression of non-alcoholic fatty liver disease (NAFLD).
Yamei Duan +6 more
semanticscholar +1 more source
TLR2 senses the SARS-CoV-2 envelope protein to produce inflammatory cytokines
Nature Immunology, 2021 The innate immune response is critical for recognizing and controlling infections through the release of cytokines and chemokines. However, severe pathology during some infections, including SARS-CoV-2, is driven by hyperactive cytokine release, or a ...
Min Zheng +7 more
semanticscholar +1 more source
The basic immunology of asthma.
Cell, 2021 In many asthmatics, chronic airway inflammation is driven by IL-4-, IL-5-, and IL-13-producing Th2 cells or ILC2s. Type 2 cytokines promote hallmark features of the disease such as eosinophilia, mucus hypersecretion, bronchial hyperresponsiveness (BHR ...
H. Hammad, B. Lambrecht
semanticscholar +1 more source
Macrophage-derived cytokines in pneumonia: Linking cellular immunology and genetics
Cytokine & growth factor reviews, 2020 Graphical ...
M. Dukhinova +4 more
semanticscholar +1 more source