Results 161 to 170 of about 163,436 (210)
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Cytokines in placental physiology
Advances in Neuroimmunology, 1991Recent studies have shown that the human placenta is a very complex organ with many properties (Petraglia et al., 1990c). It plays a very important role in the physiology of pregnancy. Among various functions, its hormonal production is one of the most relevant.
Stefano Angioni, Felice Petraglia
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Understanding Cytokines Part I: Physiology and Mechanism of Action
Biological Research for Nursing, 2000This is the first of a 2-part article on understanding cytokines. Cytokines are intercellular signaling proteins released from virtually all nucleated cells that influence growth and cellular proliferation in a wide range of tissues. Cytokines have immune modulating effects and are understood to control most of the physical and psychological symptoms ...
Elizabeth Corwin
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Cytokines and Hematopoietins: Physiology, Pathophysiology, and Potential as Therapeutic Agents
Recent Results in Cancer Research, 1991Improved understanding of host biology, immunology, and tumor pathophysiology raises the possibility of introducing new treatment modalities for cancer patients: stimulation of host defense mechanisms, including specific and nonspecific immunological approaches, as well as approaches aimed directly at altering tumor growth and differentiation by ...
François Herrmann +2 more
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Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology
Pharmacology & Therapeutics, 1996Numerous cytokines and their receptors have been identified in the brain, where they act as mediators of host defence responses and have direct effects on neuronal and glial function. Experimental tools for studying cytokine actions, their source and control of synthesis in the brain, actions and mechanisms of action will be reviewed here.
S Toulmond, N J Rothwell
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Gene Knockout: New Approach to the Physiology of Cytokines
1993Advances in the last decade in both molecular biology and mammalian embryology make it possible to study gene structure-function relationships in new ways. Cloning techniques have become routine and the body of genomically cloned genes is increasing daily.
F. F. Csaikl, U. N. Csaikl, S. K. Durum
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The Interaction of Cytokines with Stem Cell and Stromal Cell Physiology
1999It is now well established that cellular interactions between primitive haemopoietic progenitor cells (HPC) and the stromal tissue of the bone marrow (BM) play a central role in regulating haemopoiesis. Despite considerable research efforts, the precise molecular mechanisms responsible for this control remain to be fully defined.
Andrew Zannettino +2 more
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Physiological role of cytokines in the regulation of mammalian metabolism
Trends in Immunology, 2023The innate cytokine system is involved in the response to excessive food intake. In this review, we highlight recent advances in our understanding of the physiological role of three prominent cytokines, interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF), in mammalian metabolic regulation.
Axel de Baat +3 more
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Cytokines and Skeletal Physiology
Clinical Orthopaedics and Related Research, 1996Cytokines are soluble factors that play a critical role in mediating cell to cell interactions within skeletal tissues. These effects are mediated by paracrine, autocrine, and juxtacrine mechanisms. There are also examples in which the cytokines can function in an endocrine fashion.
S R, Goldring, M B, Goldring
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SOCS: physiological suppressors of cytokine signaling
Journal of Cell Science, 2000ABSTRACT Cytokines regulate cellular behavior by interacting with receptors on the plasma membrane of target cells and activating intracellular signal transduction cascades such as the JAK-STAT pathway. Suppressors of cytokine signaling (SOCS) proteins negatively regulate cytokine signaling.
D L, Krebs, D J, Hilton
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