Results 171 to 180 of about 163,436 (210)
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The Role of Cytokines in Physiological Sleep Regulation

Annals of the New York Academy of Sciences, 2001
Abstract: Several growth factors (GFs) are implicated in sleep regulation. It is posited that these GFs are produced in response to neural activity and affect input‐output relationships within the neural circuits where they are produced, thereby inducing a local state shift. These GFs also influence synaptic efficacy.
J M, Krueger   +4 more
openaire   +2 more sources

The Cytokines: Physiological and Pathophysiological Aspects

1993
Publisher Summary This chapter discusses the physiological and pathophysiological aspects of cytokines. Despite the fact that many of the molecules are described on the basis of a single biological function, several molecules subsequently turned out to be pleiotropic with a wide range of actions and target cells.
S W, Evans, J T, Whicher
openaire   +2 more sources

Humoral regulation of physiological sleep: cytokines and GHRH

Journal of Sleep Research, 1999
Interleukin‐1, tumour necrosis factor, and growth hormone releasing hormone form part of the humoral mechanisms regulating physiological sleep. Their injection enhances non‐rapid‐eye‐movement sleep whereas their inhibition reduces spontaneous sleep and sleep rebound after sleep deprivation.
J M, Krueger, F, Obál, J, Fang
openaire   +2 more sources

The carbohydrate recognition by cytokines modulates their physiological activities

Glycoconjugate Journal, 2004
A variety of cytokines have been reported to be able to recognize specific carbohydrate moieties. To date, the role of carbohydrate recognition in cytokine function has been analyzed for several cytokines, including fibroblast growth factor (FGF), tumor necrosis factor (TNF)-alpha, and interleukin (IL)-2.
Katsuko, Yamashita, Keiko, Fukushima
openaire   +2 more sources

Autocrine secretion and the physiological concentration of cytokines

Immunology Today, 1996
Abstract In contrast to hormones, cytokine activities are often purely local and, consequently, their active physiological concentration is hard to define. Here, using IL-2 as an example, David Kaplan proposes that the local concentrations of cytokines might be much greater than expected.
openaire   +2 more sources

Physiology of cytokine pathways in rheumatoid arthritis

Arthritis & Rheumatism, 2001
This review has summarized the physiology of some cytokine pathways in RA, emphasizing the redundant and synergistic nature of this network. However, it is important to understand that this system is self-regulating through the action of anti-inflammatory cytokines, opposing cytokines, cytokine receptor antagonists, and possibly naturally occurring ...
openaire   +2 more sources

The potential relevance of cytokines to ovarian physiology

The Journal of Steroid Biochemistry and Molecular Biology, 1992
Elucidating the secrets of intraovarian intercellular communication constitutes a central area of investigation. While most attention has been directed thus far at the somatic cellular components of the ovary, the potential role(s) and relative importance of the resident ovarian white blood cell have received relatively limited attention.
openaire   +2 more sources

[Cytokines and pregnancy: physiology].

Journal de gynecologie, obstetrique et biologie de la reproduction, 1992
Several biological systems originating in the fetus and in the mother are involved in embryo implantation, maintenance of the pregnancy, protection of the fetus against outside influences and the start of labour (these are the immune system, endocrine system, and the endothelial system).
D, Vinatier   +5 more
openaire   +1 more source

Immunosuppressants: Tools to investigate the physiological role of cytokines

BioEssays, 1993
AbstractThe cyclic opeptide Cyclosporinee A (CsA) is best known as the immunosuppressive drug which has revoulutionized organ transplantation. It selectively suppresses T cell activation by blocking the transcription of cytokine genes such as IL‐2 at the level of transxcription factor modulation.
openaire   +2 more sources

Carbohydrate Recognition by Cytokines and its Relevance to their Physiological Activities

2007
Cytokines regulate the immune response, inflammation, cell proliferation and differentiation as mediators of the regulatory network among lymphoid cells, hematopoietic cells, and endothelial cells. Many signal transduction mechanisms are evoked after cytokines bind to their respective receptors.
Keiko Fukushima, Katsuko Yamashita
openaire   +1 more source

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