Results 191 to 200 of about 166,640 (259)

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Inter-Organ Communication Networks in Systemic Physiology: Glucocorticoid Receptor α as a Central Integrator of Homeostasis. [PDF]

Int J Mol Sci
Meduri GU.
europepmc   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Effects of MDMA treatment and cessation on sexual behaviour and testicular functions in male sprague-dawley rats. [PDF]

BMC Pharmacol Toxicol
Obembe OO, George ET, Mustapha RA, Akhigbe RE.   +3 more
europepmc   +1 more source

Physiology and Pathology of Cytokine: Commercial Production and Medical Use

, 2017
Nemanja Zdravkovic, Mirko Rosic, Mitar Lutovac, Vladimir Zdravkovic   +3 more
openaire   +2 more sources

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Mechanisms of IL-17A Neutralisation in Alleviating Renal Fibrosis and Inflammation in Spontaneously Hypertensive Rats. [PDF]

Clin Exp Pharmacol Physiol
Ba A, Chen Z, Wu M, Li W, Wang Y.
europepmc   +1 more source

β-Hydroxybutyrate attenuates bronchial smooth muscle proinflammatory cytokine production and contraction. [PDF]

Am J Physiol Cell Physiol
Fastiggi VA, Mank MM, Caporizzo MA, Poynter ME.   +3 more
europepmc   +1 more source

Editorial: Endometrial health and disease: from molecular insights to clinical advances. [PDF]

Front Vet Sci
Amaral A, Piotrowska-Tomala K, Kordowitzki P.   +2 more
europepmc   +1 more source