Results 131 to 140 of about 179,487 (293)
Lymphocytotoxic antibodies in spontaneous cytomegalovirus infection. [PDF]
, 1978 M Jeannet, Hanspeter Stalder
openalex +1 more source
Advanced Science, EarlyView.Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng +10 more
wiley +1 more source
Advanced Science, EarlyView.βFaar selectively targets and inhibits the GTPase activity of the RAB18 protein, thereby reducing LD volume. Conversely, βFaar promotes nuclear translocation of the transcription factor IRF4 in inguinal white adipose tissue (iWAT), facilitating the browning of white adipose tissue and attenuating body fat accumulation.
Yue Yang +13 more
wiley +1 more source
Advanced Science, EarlyView.Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra +9 more
wiley +1 more source
Alteration of host defense mechanisms by murine cytomegalovirus infection [PDF]
, 1977 D K Kelsey +3 more
openalex +1 more source
BRD4 Signaling Maintains the Differentiated State of β Cells
Advanced Science, EarlyView.The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu +22 more
wiley +1 more source
Immunoperoxidase technique for detection of antibodies to human cytomegalovirus [PDF]
, 1976 Giuseppe Gerna +2 more
openalex +1 more source
The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression
Advanced Science, EarlyView.Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu +5 more
wiley +1 more source
Ulcerative Esophagitis Caused by Cytomegalovirus During Infectious Mononucleosis in a Young and Immunocompetent Male Patient-A Case Report. [PDF]
Clin Case RepApostolski D +4 more
europepmc +1 more source