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Cytomegalovirus Infections

Pediatrics In Review, 1981
It has been 25 years now since the first strains of cytomegalovirus (CMV) were isolated. At that time, and for several years thereafter, the infection was recognized as the cause of a rare and severe congenital infection referred to as cytomegalic inclusion disease (CID).
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Cytomegalovirus Infections

Seminars in Pediatric Neurology, 2012
Human cytomegalovirus, a human herpesvirus, remains a major cause of neurological disorders as a consequence of infections acquired in utero or postnatally. This article summarizes current information regarding the epidemiology, clinical manifestations, treatment, and prevention of this ubiquitous human infection.
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Diagnosis of Cytomegalovirus Infection

Clinical Infectious Diseases, 1988
Diagnostic procedures for documenting cytomegalovirus (CMV) infection include culture, cytology, serology, and the detection of CMV antigens and/or nucleic acids within infected tissues. Each procedure is useful, but each has specific pitfalls. A positive urine, blood, or genital culture confirms CMV infection but does not prove that CMV is causing a ...
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Congenital cytomegalovirus infections

Seminars in Fetal and Neonatal Medicine, 2007
Congenital cytomegalovirus (CMV) infection is one of the most common viral causes of congenital infections in high resource countries and a leading cause of hearing loss as well as an important contributor to neurodevelopmental disabilities in children.
Gunilla, Malm, Mona-Lisa, Engman
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Congenital Cytomegalovirus Infection

New England Journal of Medicine, 2018
Congenital Cytomegalovirus Infection A pregnant 35-year-old woman underwent routine fetal ultrasonography that revealed ventriculomegaly. After delivery, testing confirmed congenital CMV infection in the newborn.
Kenta, Kawai, Hiroaki, Itoh
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Treatment of Cytomegalovirus Infection

Clinics in Laboratory Medicine, 1987
CMV infection is a major cause of morbidity and mortality in the immune compromised host. Ganciclovir and phosphonoformate have in vitro and in vivo activity against human CMV, and controlled trials of both these drugs in immunocompromised patients have suggested their efficacy.
E C, Reed, J D, Meyers
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Epidemiology of Cytomegalovirus Infections

Clinical Infectious Diseases, 1990
The determinants of cytomegalovirus (CMV) infection and disease can now be understood from studies of newborns, recipients of organ or bone marrow transplants, subjects infected with human immunodeficiency virus, and recipients of blood transfusions. CMV is transmitted to the neonate transplacentally, by passage through a contaminated birth canal, or ...
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Cytomegalovirus infection of the skin

The American Journal of Dermatopathology, 1982
A case of fatal generalized cytomegalovirus infection with particular attention to lesions involving the skin is reported. Characteristic cytomegalovirus inclusion bodies were present within nuclei of endothelial cells in the dermis beneath ulcerations. Skin biopsy may be useful in the diagnosis of disseminated infections by cytomegalovirus.
J D, Walker, T M, Chesney
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Cytomegalovirus infections and the skin

Journal of the American Academy of Dermatology, 1988
Cytomegalovirus has received renewed recognition as a pathogen in recent years. This article emphasizes the cutaneous manifestations of cytomegalovirus infection.
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Cytomegalovirus infection in pregnancy

Journal of Virological Methods, 1987
Cytomegalovirus (CMV) is the most common agent of prenatal (peri- and early postnatal) infection of the newborn with an incidence of 0.2-2.0% (5-10%) depending on the socio-economic status. Only one out of 20 congenitally CMV-infected newborns shows serious symptoms. Another two may reveal mental retardation and other significant handicaps in later age.
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