Results 41 to 50 of about 953,563 (287)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Asymptomatic cytomegalovirus gastritis in an immunocompetent COVID-19 patient: a case report

Journal of the Pakistan Medical Association
A number of complications are associated with COVID-19 due to reduced immunity. Of these, opportunistic infections are of great significance because of their atypical presentation and low detection rates.
Fizza Najeeb, Maria Iqbal, Syed Mohammad Mehmood Abbas, Tahir Iqbal   +3 more
doaj   +1 more source

A Lupus Hepatitis Case and its Association with Igm Antibodies against Cytomegalovirus, Herpes Simplex and Herpes Zoster Viruses

European Journal of Inflammation, 2009
The hypothesis for a role of viral infections on the pathogenesis of systemic lupus erythematosus has been discussed in many works, particularly that of cytomegalovirus and Epstein Barr virus infections as trigger of autoimmune processes.
A. Riccio MD, G. Morelli, M.G. Sangiolo, R. Morante, C. Esposito, G. Tarantino   +5 more
doaj   +1 more source

Prevalence of Cytomegalovirus Infection among Suspected Infants in Baghdad

مجله كليه طب الكندي, 2022
Background: Cytomegalovirus (CMV) virus is a recognized important cause of congenital CMV infection which carries a significant risk for symptomatic disease and developmental defects in newborns.
Tareef Fadhil Raham, Ahmed Nabeel Abdul-Wahab, Zainab Ali Chaloub   +2 more
doaj   +1 more source

Natural killer cells promote early CD8 T cell responses against cytomegalovirus. [PDF]

, 2007
Understanding the mechanisms that help promote protective immune responses to pathogens is a major challenge in biomedical research and an important goal for the design of innovative therapeutic or vaccination strategies.
Sacher, Torsten, Ulrich H Koszinowski, Rupp Brigitte, Eric Vivier, Ruzsics, Zsolt, Koszinowski Ulrich H, Cornillon, Amélie, Dalod Marc, Bessou Gilles, Koszinowski, Ulrich H, Marc Dalod, Sacher Torsten, Robbins, Scott H., Torsten Sacher, Tomasello Elena, Dalod, Marc, Scott H Robbins, Nicolas Zucchini, Ruzsics Zsolt, Koszinowski, Ulrich H., Zsolt Ruzsics, Elena Tomasello, Gilles Bessou, Bessou, Gilles, Tomasello, Elena, Cornillon Amélie, Vivier Eric, Vivier, Eric, Zucchini, Nicolas, Amélie Cornillon, Brigitte Rupp, Zucchini Nicolas, Robbins, Scott H, Robbins Scott H, Rupp, Brigitte   +34 more
core   +2 more sources

Clinical Characteristics and Concordance of Anti‐MDA5 Antibodies: A Multicenter Australian Study

Arthritis Care &Research, EarlyView.
Objective In Australia, anti‐MDA5 antibodies are exclusively tested by a line immunoblot assay (LIA). The clinical concordance of an LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies. Methods Electronic records of a multisite cohort (patients
Syed B. Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source

Belatacept associated - cytomegalovirus retinitis in a kidney transplant recipient: a case report and review of the literature

BMC Ophthalmology, 2020
Background To report the first case of belatacept-associated multidrug-resistant Cytomegalovirus retinitis in a kidney transplant recipient. Case presentation A 76-year-old African male renal allograft recipient was admitted for acute visual loss of the ...
Pierre-Guillaume Deliège, Justine Bastien, Laetitia Mokri, Charlotte Guyot-Colosio, Carl Arndt, Philippe Rieu   +5 more
doaj   +1 more source

Report from the second cytomegalovirus and immunosenescence workshop. [PDF]

, 2011
The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory frequency, inflation and immunosenescence;
Pawelec, Graham, R Macualay (16139510), van Lier, R, Paul Klenerman, Rafael Solana, Beswick, M, Mason Gavin, Goronzy Joerg, Westendorp Rudi, Maier, Andrea B., Akbar, A, Mason, Gavin, Herndler-Brandstetter Dietmar, Wang, George, A B Maier (13318254), Delphine Sauce, David Melzer, Pachnio, A., Kern, F, Caruso Calogero, J Sinclair (7750493), Caruso, C, Gkrania-Klotsas, Effrossyni, A. B. Maier, A Akbar (12141924), Solana, R., Arne Akbar, Bosch, Jos A, Sansoni, Paolo, Henson, SM, Macallan, D., Moss P., Gkrania-Klotsas, E, Henson, S, Dutta, A, Vescovini Rosanna, Macallan D., Morgan M., Macualay, Richard, Mark Beswick, Maier, AB, Hill A., Nikolich-Zugich, J, Fulop, Tamas, Pachnio, A, Wills, M., D. Macallan, Westendorp, Rudi, Giuseppina Colonna-Romano, Melzer D., J Nikolich-Zugich (16139513), Sinclair, J, Mason G., Pachnio, Annette, A. Hill, C. Franceschi, Klenerman, Paul, Wang, G, Sansoni P., Kern, Florian, A. Akbar, G. Colonna Romano, Goronzy, J., Riddell Natalie, E Gkrania-Klotsas (16139495), Griffiths, SJ, Solana Rafael, Graham Pawelec, Bosch Jos A, P. Trzonkowski, P Trzonkowski (16139528), Hill, A., Morgan, Matthew, D Sauce (16139522), Mason, G., Franceschi, C, Riddell, N., D. Melzer, Tamas Fulop, Melzer, D, Wills, Mark, G Colonna-Romano (16139489), Sinclair J., Rene van Lier, Henson, Sian M., CARUSO, Calogero, Dutta, Ambarish, Nikolich-Zugich, J., Sauce, D., S. Henson, Hill, Ann, Caruso, C., Pawelec G., Florian Kern, Kern Florian, Riddell, Natalie, Wills, M, D Melzer (14728009), Gkrania Klotsas, E, Fulop, T., Klenerman, P., J. Goronzy, Trzonkowski Piotr, Jan Strindhall, J. Strindhall, Fulop Tamas, Sansoni, P, Nikolich-Zugich Janko, Janko Nikolich-Zugich, Herndler-Brandstetter, D, Herndler Brandstetter D., Goronzy, Joerg, Colonna-Romano Giuseppina, Akbar, Arne, N. Riddell, Sauce, D, Piotr Trzonkowski, R. Westendorp, Bosch, JA, Jos A Bosch, T Fulop (16139363), Derek Macallan, M. Wills, Griffiths, S.J., R. van Lier, Roberts R., M Beswick (16139483), Melzer, David, Fulop T., Richard Macaulay, Ryan Roberts, Griffiths, Stephen J, C Caruso (16139357), Wang George, van Lier R., Macualay, R, Franceschi, Claudio, P Moss (7787393), Macaulay, R, George Wang, Akbar Arne, J A Bosch (16139486), M. Morgan, Moss Paul, Solana R., Florian Kern (4461943), Gkrania-Klotsas, E., Westendorp R., Trzonkowski, P, J Goronzy (16139498), Rudi Westendorp, Klenerman P., F. Kern, van Lier Rene, Natalie Riddell, P. Moss, Caruso C., Pawelec, G, Strindhall J., R van Lier (16139531), P. Klenerman, Sauce D., Macaulay, Richard, Gkrania Klotsas E., R Vescovini (16139534), Nikolich Zugich, J, Stephen J Griffiths, Akbar, A., Strindhall, J, Sauce, Delphine, Beswick, Mark, Annette Pachnio, Maier, Andrea, Colonna-Romano, Giuseppina, Griffiths Stephen J, N Riddell (16139516), J. Nikolich Zugich, Dutta A., Nikolich-Zugich, Janko, G. Mason, Nikolich Zugich J., Moss, Paul; id_orcid, Macaulay Richard, Roberts, R., M Wills (13757002), Wills M., Franceschi Claudio, Strindhall, Jan, Akbar A., Kern, F., Riddell N., Effrossyni Gkrania-Klotsas, Dutta Ambarish, Pawelec, G., Henson S., A. Pachnio, Colonna-Romano, G., D Macallan (16139381), Joerg Goronzy, Melzer David, M. Beswick, Goronzy, G, Gavin Mason, Colonna Romano G., Sansoni, P., R Roberts (7710605), Goronzy, J, Moss, P, A Pachnio (1928), Klenerman Paul, COLONNA ROMANO, Giuseppina, Morgan Matthew, Vescovini, Rosanna, Melzer, D., T. Fulop, Klenerman, P, Vescovini R., P Sansoni (16139519), D Herndler-Brandstetter (16139507), Sinclair, John, Hill, A, Bosch J. A., P Klenerman (14557544), G Wang (7291427), Pachnio A., van Lier, Rene, Lier, R. van, John Sinclair, Rosanna Vescovini, Macallan, D, Roberts Ryan, Bosch, Jos A., Henson Sian M, Maier A. B., Sinclair John, Griffiths, Stephen J., Paul Moss, Maier, Andrea B, Maier Andrea B, Macallan, Derek, Gkrania-Klotsas Effrossyni, Macaulay, R., Vescovini, R, Morgan, M., Hill Ann, Maier, A.B., Sinclair, J., Pachnio Annette, Paolo Sansoni, Riddell, N, Beswick Mark, Trzonkowski P., Kern F., G. Wang, A Hill (7707728), Herndler-Brandstetter, Dietmar, R Solana (16139525), Griffiths, Stephen, Vescovini, R., Westendorp, R., C Franceschi (16139492), G Mason (15968855), J. Sinclair, Matthew Morgan, A. Dutta, Wills Mark, Moss, Paul, Sian M Henson, Bosch, Jos, Beswick, M., Mason, G, Sauce Delphine, G. Pawelec, Franceschi, C., S. J. Griffiths, R. Roberts, D. Sauce, Goronzy J., Wills1, M, Maier, Andrea B.; id_orcid, Henson, S.M., Moss, P., Strindhall Jan, Trzonkowski, P., Fulop, T, Macualay R., Westendorp, R, R. Macualay, Solana, R, Trzonkowski, Piotr, Ambarish Dutta, Jos Bosch, Mark Wills, Bosch, J.A., Henson, Sian, Dietmar Herndler-Brandstetter, Ann Hill, C. Caruso, Dutta, A., Beswick M., Andrea B Maier, Sansoni Paolo, Herndler Brandstetter, D, G Pawelec (16139351), Calogero Caruso, M Morgan (7738241), Pawelec Graham, Dietmar Herndler-br, Wang G., A Dutta (11812487), E. Gkrania Klotsas, Herndler-Brandstetter, D., Wang, G., Roberts, Ryan, J. A. Bosch, D. Herndler Brandstetter, J Strindhall (16139387), Macallan Derek, S J Griffiths (16139501), Griffiths S. J., R. Solana, Solana, Rafael, S Henson (16139504), Roberts, R, Colonna-Romano, G, Claudio Franceschi, Strindhall, J., Morgan, M, R Westendorp (16139537)   +328 more
core   +3 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source