Results 251 to 260 of about 1,097,210 (332)
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma +5 more
wiley +1 more source
CD318 expression defines a novel subset of human CD8<sup>+</sup> regulatory T cells. [PDF]
Do JS +8 more
europepmc +1 more source
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
wiley +1 more source
Cell State Transitions Drive the Evolution of Disease Progression in B-Lymphoblastic Leukemia. [PDF]
Gravenmier C +7 more
europepmc +1 more source
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae +9 more
wiley +1 more source
Correction: Jaksic Karisik et al. JQ1 Treatment and miR-21 Silencing Activate Apoptosis of CD44+ Oral Cancer Cells. <i>Int. J. Mol. Sci.</i> 2025, <i>26</i>, 1241. [PDF]
Jaksic Karisik M +5 more
europepmc +1 more source

