Results 261 to 270 of about 937,182 (344)

Viable and Functional: Long-Term -80 °C Cryopreservation Sustains CD34⁺ Integrity and Transplant Success. [PDF]

J Clin Med
Pinar IE, Sahin M, Gursoy V, Ersal T, Budak F, Ozkocaman V, Ozkalemkas F.   +6 more
europepmc   +1 more source

Synergistic Combination of Tamoxifen–Tetraphenylethylene Co‐Assembled Micelles and Orlistat‐Induced Lipid Droplet Inhibition to Overcome Tamoxifen Resistance

Advanced Healthcare Materials, EarlyView.
Molecule 2, which contains a shorter oligoether chain, binds to tamoxifen via structural similarity forming micelles with a positive surface charge, thereby enhancing cellular uptake. These fluorescent micelles induce lipid droplet (LD) accumulation, exhibit strong fluorescence, and effectively overcome tamoxifen resistance by synergizing with orlistat‐
Jung Yeon Park, Jeehee Lee, Young Yong Kim, Sanghee Lee, Yongju Kim   +4 more
wiley   +1 more source

Sequential factor delivery enables efficient workflow for universal gene editing in clinical grade iPS cells. [PDF]

Sci Rep
Berger T, Borisova E, Gamerschlag A, Terheyden-Keighley D, Martins S, Greber B.   +5 more
europepmc   +1 more source

Coordinated Development of Immune Cell Populations in Vascularized Skin Organoids from Human Induced Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Vascularized skin organoids are developed from human induced pluripotent stem cells and contain macrophages, Langerhans cells, and neutrophils. Vascularized skin organoids offer a transformative platform to model skin biology and enable mechanistic investigations of inflammatory and hematologic skin disorders.
Mitchell Mostina, Jane Sun, Seen Ling Sim, Imaan A. Ahmed, Fernando Souza‐Fonesca‐Guimaraes, Ernst J. Wolvetang, Jason Brown, Snehlata Kumari, Kiarash Khosrotehrani, Abbas Shafiee   +9 more
wiley   +1 more source

Iron Deficiency Drives Th2-Mediated Immunity in Pediatric Atopic Dermatitis Through DNA Hypermethylation and TIGIT Suppression in IL-10-Producing Breg Cells. [PDF]

J Asthma Allergy
Gao X, Hou Z, Li X, Ouyang T, Yu S, Wang Y, Zhang G, Luo Y, He X, Liao W, Wei Z.   +10 more
europepmc   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Evaluating DAPI stain to assess sperm membrane integrity by flow cytometry in livestock species. [PDF]

Vet Res Commun
Martínez-Rodrigo L, Gacem S, Brüggemann M, Pinto S, Mocé E, Serrano-Jara D, García ML, Yániz JL, Silvestre MA.   +8 more
europepmc   +1 more source

Photoactivated Proximity Protein Labeling Reveals Enhanced Tumor Retention of a D‐Peptide‐Ruthenium Prodrug Conjugate

Advanced Healthcare Materials, EarlyView.
Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang, Peiyuan Wang, Hildert Bronkhorst, Yurii Husiev, Ludovic Bretin, Maarten N. van Ginkel, Wen Sun, Sylvestre Bonnet   +7 more
wiley   +1 more source

Chronic inflammatory demyelinating polyneuropathy (CIDP) after cilta-cel therapy. [PDF]

Blood Cancer J
Korenkov M, Liebaert J, Yousefian S, Schwartz S, Demel UM, Braune J, Odabasi MC, Herzberg L, Böckle D, Görür NC, V Landenberg-Roberg V, Bohl S, Tregel E, Hennig S, Franke C, Haas S, Keller U, Krönke J, Busse A.   +18 more
europepmc   +1 more source

FLOW CYTOMETRY IN URINARY TRACT MALIGNANCIES

, 1982
Takeshi Matsuura, Takahiro Akiyama, Takashi Kurita   +2 more
openalex   +2 more sources