Results 261 to 270 of about 615,339 (319)
Engineering Saccharomyces boulardii for enhanced surface display capacity. [PDF]
Xu L+6 more
europepmc +1 more source
This study elucidates the crosstalk between tumor‐associated macrophages (TAMs) and anaplastic thyroid cancer stem cells (ATCSCs). The findings reveal that CCL20 from THP‐1‐M2 activates the IRAK‐1/NF‐κB1/2 pathway in ATCSCs, thereby enhancing CXCL5 secretion.
Qi Liu+11 more
wiley +1 more source
Detecting ectopic thymus in thymoma-associated myasthenia gravis through flow cytometry analysis of CD3<sup>medium</sup>TCRvβ<sup>medium</sup>CD4<sup>+</sup>CD8<sup>+</sup> T cells and its clinical significance. [PDF]
Ao Y+19 more
europepmc +1 more source
A ROS‐driven in situ oxygen supply nanoventilator based on enzyme nanocapsule can convert ROS into O2 through enzyme cascade reaction between SOD and CAT to relieve lung hypoxia, and kill MRSA by releasing vancomycin, which effectively reduces HIF‐1α expression and balances pro‐inflammatory/anti‐inflammatory macrophages ratio, thereby reducing the ...
Zheng Luo+7 more
wiley +1 more source
<i>Porphyromonas gingivalis</i> exacerbates experimental autoimmune encephalomyelitis by driving Th1 differentiation via ZAP70/NF-κB signaling. [PDF]
Dai D+7 more
europepmc +1 more source
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells
Through a combination of transcriptomic and histone mapping studies integrated with chromatin imaging, we define how chromatin organization in nanoscale packing domains fine tunes the plasticity of cancer stem cells (CSCs) driving evasion from and survival after chemotherapy.
Yinu Wang+20 more
wiley +1 more source
ASO-mediated knock-down of GPNMB in mutant-GRN and in Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses. [PDF]
Wallings RL+8 more
europepmc +1 more source