Results 81 to 90 of about 5,295 (175)

In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease [version 8; peer review: 2 approved, 2 approved with reservations]

F1000Research
Background Recent evidence suggests that some flavonoid compounds obtained from crude methanol extract of mistletoe leaves (Dendrophthoe pentandra L. Miq), also known as Benalu Duku (BD), have antimicrobial effects.
Lazuardi Mochamad, Selvaraja Malarvili, Khairat Jasmine, Vuanghao Lim   +3 more
doaj   +1 more source

A stably expressed llama single-domain intrabody targeting Rev displays broad-spectrum anti-HIV activity

, 2014
The HIV Rev protein mediates the transport of partially and unspliced HIV mRNA from the nucleus to the cytoplasm. Rev multimerizes on a secondary stem-loop structure present in the viral intron-containing mRNA species and recruits the cellular ...
Vandamme, Anne-Mieke, Pannecouque, Christophe, Daelemans, Dirk, Boons, Eline, Li, Guangdi, Vercruysse, Thomas, Vanstreels, Els   +6 more
core   +1 more source

Molluscum contagiosum virus expresses late genes in primary human fibroblasts but does not produce infectious progeny

, 2001
Molluscum contagiosum virus (MCV), a member of the family Poxviridae, can be isolated from skin-lesion material of patients with molluscum contagiosum infection. MCV replicates efficiently in human keratinocytes in vivo but viral replication has not been
Kehm, R., Melquiot, N., Bugert, Joachim Jakob   +2 more
core   +1 more source

Antiviral activity of iridoid glycosides extracted from Fructus Gardeniae against influenza A virus by PACT-dependent suppression of viral RNA replication

, 2020
Epidemic and pandemic influenza A virus (IAV) poses a significant threat to human populations worldwide. Iridoid glycosides are principal bioactive components from the Gardenia jasminoides J.
Li, Chun, Bao, Lei, Zhao, Ronghua, Cui, Xiaolan, Guo, Shanshan, Sun, Jing   +5 more
core   +1 more source

The Indirect Effect of BVDV on Immune Suppression: The Role of Infected Macrophages in Lymphocyte Apoptosis

, 2017
BVDV is an important pathogen of cattle that affects both the dairy and beef industry causing severe economic losses. The main problem of BVDV is the immune suppression that is associated with lymphoid depletion shortly post infection.
Abdelsalam, Karim
core  

Emergence of a new rhabdovirus associated with mass mortalities in eelpout (Zoarces viviparous) in the Baltic Sea

, 2017
We report the first description of a new Rhabdoviridae tentatively named eelpout rhabdovirus (EpRV genus Perhabdovirus). This virus was associated with mass mortalities in eelpout (Zoarces viviparous, Linnaeus) along the Swedish Baltic Sea coast line in ...
Valarcher, J.-F., Alfjorden, A., Hagstrom, A.E., Leijon, M., Ljunghager, F., Juremalm, M., Olesen, Niels Jørgen, Axen, C., Blomkvist, E., Boutrup, Torsten Snogdal, Hakhverdyan, M.   +10 more
core   +1 more source

Cytopathogenicity of classical swine fever virus caused by defective interfering particles

, 1995
For three independent cytopathogenic isolates of classical swine fever virus, defective RNAs were found in infected cells in addition to full-length viral genomes.
Thiel, H. J., Meyers, Gregor
core  

Interferon, virus vaccines and antiviral drugs

, 2008
The emergence of viruses with zoonotic potential, i.e. with the potential ability to cross species barriers to infect unnatural hosts, poses a huge threat to humans.
Rodrigues, Ana Mara Lopes
core  

Porcine cells persistently infected with classical swine fever virus protected from pestivirus-induced cytopathic effect

, 1998
Cytopathogenicity of classical swine fever virus (CSFV) depends on the presence of defective particles containing a subgenomic (sg) RNA with a defined deletion.
Jon-duri Tratschin, Martin A. Hofmann, Christian Moser, Christian Mittelholzer   +3 more
core  

Gelatinase B/matrix metalloproteinase-9 cleaves interferon-β and is a target for immunotherapy

, 2003
Parenteral administration of interferon (IFN)-b is one of the currently approved therapies for multiple scler-osis. One characteristic of this disease is the increased production of gelatinase B, also called matrix metallo-proteinase (MMP) 9.
Philippe E. Van Den Steen, Isabelle Ronsse, Ghislain Opdenakker, Erik Martens, Paul Proost, Inge Nelissen   +5 more
core   +1 more source