Results 161 to 170 of about 1,082,029 (359)

Hormones and liver cytoplasm. 3. Succinic dehydrogenase, nucleases and ‘polymerized’ ribonucleic acid as affected by hypophysectomy, growth-hormone treatment and adrenalectomy [PDF]

, 1956
Barbara M. Stevens, E. Emmet Reid
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Pre-ribosomal particles from nucleoli to cytoplasm

Nucleus
The analysis of nucleocytoplasmic transport of proteins and messenger RNA has been the focus of advanced microscopic approaches. Recently, it has been possible to identify and visualize individual pre-ribosomal particles on their way through the nuclear ...
Ulrich Kubitscheck, Jan Peter Siebrasse
doaj   +1 more source

Hormones and liver cytoplasm. 5. Enzymes concerned in nucleic-acid catabolism, as affected by hypophysectomy or adrenalectomy [PDF]

, 1958
E. Emmet Reid, Barbara M. Stevens
openalex   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
wiley   +1 more source

Coupling of cytoplasm and adhesion dynamics determines cell polarization and locomotion

, 2009
Observations of single epidermal cells on flat adhesive substrates have revealed two distinct morphological and functional states, namely a non-migrating symmetric unpolarized state and a migrating asymmetric polarized state.
Alt, Wolfgang, Bock, Martin, Möhl, Christoph   +2 more
core  

Defeating Cytoplasmic Sequestration of p53 in Human Breast Cancer Cells; Is Mortalin Involved? [PDF]

, 2012
Cytoplasmic sequestration of p53, possibly caused by p53 interacting with mortalin, can prevent p53 from functioning in DNA repair and apoptosis, causing aberrant growth.
Yunes, Sarah
core   +1 more source

Hormonal influences on the incorporation of injected precursors into the protein and ribonucleic acid of liver cytoplasm [PDF]

, 1956
E. Emmet Reid, M. A. O'Neal, Barbara M. Stevens, V. C. E. Burnop   +3 more
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Effect of a carcinogenic AZO dye on radio-phosphorus turnover in rat-liver nuclei and cytoplasm [PDF]

, 1951
A. Clark Griffin, Lew Cunningham, Eugenia L. Brandt, Donald W. Kupke   +3 more
openalex   +1 more source