Results 161 to 170 of about 1,300,822 (378)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Absence of Mutagenic Action of X-Rayed Cytoplasm in Habrobracon [PDF]

, 1950
Anna R. Whiting
openalex   +1 more source

Defeating Cytoplasmic Sequestration of p53 in Human Breast Cancer Cells; Is Mortalin Involved? [PDF]

, 2012
Cytoplasmic sequestration of p53, possibly caused by p53 interacting with mortalin, can prevent p53 from functioning in DNA repair and apoptosis, causing aberrant growth.
Yunes, Sarah
core   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence

Cell, 2019
Gabriel E. Neurohr, Rachel L. Terry, Rachel L. Terry, Jette Lengefeld, Megan E. Bonney, Megan E. Bonney, G. Brittingham, Fabien Moretto, Teemu P. Miettinen, Teemu P. Miettinen, L. P. Vaites, L. M. Soares, J. Paulo, J. Harper, S. Buratowski, S. Manalis, F. J. V. Werven, L. Holt, A. Amon   +18 more
semanticscholar   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Pre-ribosomal particles from nucleoli to cytoplasm

Nucleus
The analysis of nucleocytoplasmic transport of proteins and messenger RNA has been the focus of advanced microscopic approaches. Recently, it has been possible to identify and visualize individual pre-ribosomal particles on their way through the nuclear ...
Ulrich Kubitscheck, Jan Peter Siebrasse
doaj   +1 more source

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer's Disease Neurons by Imposed External Cys/CySS Redox Shifts. [PDF]

, 2019
Redox systems including extracellular cysteine/cystine (Cys/CySS), intracellular glutathione/oxidized glutathione (GSH/GSSG) and nicotinamide adenine dinucleotide reduced/oxidized forms (NADH/NAD+) are critical for maintaining redox homeostasis. Aging as
Brewer, Gregory J, Digman, Michelle A, Dong, Yue, Sameni, Sara   +3 more
core  

Differential m6A, m6Am, and m1A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.

Molecules and Cells, 2018
Jiangbo W, Fange Liu, Zhike Lu, Qili Fei, Yuxi Ai, P. He, Hailing Shi, X. Cui, R. Su, A. Klungland, G. Jia, Jianjun Chen, Chuan He   +12 more
semanticscholar   +1 more source