Microbubble‐Controlled Delivery of Biofilm‐Targeting Nanoparticles to Treat MRSA Infection
Here, an effective strategy using microbubble (MB)‐controlled delivery of biofilm‐targeting nanoparticles (BTNs) for removal and therapy of methicillin‐resistant Staphylococcus aureus (MRSA) biofilm infections is introduced. In vivo delivery of MB with BTN is demonstrated to silence key bacterial genes involved in biofilm formation (icaA), bacterial ...
Ju Yeon Chung +6 more
wiley +1 more source
Low-mass zinc pools in Escherichia coli: Micromolar concentrations, diverse compositions, and Zn-glutathione dominating under Zn-replete conditions. [PDF]
Kreinbrink AC +3 more
europepmc +1 more source
THE EFFECT OF PROTEIN SYNTHESIS INHIBITION ON THE ENTRY OF MESSENGER RNA INTO THE CYTOPLASM OF SEA URCHIN EMBRYOS [PDF]
Brigid Hogan, Paul R. Gross
openalex +1 more source
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer +7 more
wiley +1 more source
The Distribution of <i>Neospora caninum</i> Secretory Proteins in Mouse and Calf Brains. [PDF]
Ushio-Watanabe N +5 more
europepmc +1 more source
Induction of Polyoma DNA Synthesis by Injection into Frog‐Egg Cytoplasm [PDF]
Ronald A. Laskey, J. B. Gurdon
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
Granular Cell Tumor of the Dorsal Tongue in a 58-Year-Old Woman: A Case Report. [PDF]
Vlachodimitropoulos A +4 more
europepmc +1 more source

