Results 301 to 310 of about 1,316,167 (378)

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Influenza A virus subverts the LC3-pericentrin dynein adaptor complex for host cytoplasm entry. [PDF]

Sci Adv
Cong Y, Verlhac P, Green BB, de Vries-Idema J, Strauss LM, Río-Bergé C, Etzerodt A, Nejsum LN, Huckriede ALW, Reggiori F.   +9 more
europepmc   +1 more source

3D‐Printed Scaffolds Promote Enhanced Spinal Organoid Formation for Use in Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
3D‐printed organoid scaffolds with microscale channels are developed to enhance spinal cord injury recovery by guiding region‐specific spinal neural progenitor cells. These scaffolds promote axonal growth, cell maturation, and neuronal network formation.
Guebum Han, Nicolas S. Lavoie, Nandadevi Patil, Olivia G. Korenfeld, Hyunjun Kim, Manuel Esguerra, Daeha Joung, Michael C. McAlpine, Ann M. Parr   +8 more
wiley   +1 more source

Ribosomal L12 stalks recruit elongation factors to speed protein synthesis in Escherichia coli. [PDF]

Commun Biol
Hofmann JL, Yang TS, Sunol AM, Zia RN.
europepmc   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Ectopic adrenal tissue in the ovary: An incidental finding in a middle-aged woman-A case report. [PDF]

Int J Surg Case Rep
Gharib M, Karimi M, Kamali S, Mashoufi R, Mashoufi R, Ramezani F.   +5 more
europepmc   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

Advanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla, Vincenzo Verdi, Willemijn de Voogt, Mariona Estapé Sentí, Arnold C. Koekman, Julian Rietveld, Sven van Kempen, Qiangbing Yang, Juliette van Merris, Guido Jenster, Martin E. van Royen, Marcel H. Fens, Sander A. A. Kooijmans, Wytske M. van Weerden, Guillaume van Niel, Pieter Vader, Raymond M. Schiffelers   +16 more
wiley   +1 more source

Cytological Assessment of Metastatic Gastrointestinal Stromal Tumor in Ascitic Fluid. [PDF]

Diagn Cytopathol
Sultan H, Sadeghian Z, Goez-Gutierrez E, Diacovo MJ, Yoon E.   +4 more
europepmc   +1 more source

Synthetic Antiferromagnetic Designer Nanodisks for High‐Performance Magnetic Separation

Advanced Healthcare Materials, EarlyView.
Micromagnetic‐modeling‐based design and scalable fabrication of synthetic antiferromagnet (SAF) magnetic disk particles (MDPs) using sputter deposition enable high‐performance magnetic separation. The SAF MDPs achieve high colloidal stability and magnetic responsiveness and enable efficient magnetic separation, outperforming conventional particles ...
Subas Scheibler, Sebastian Habermann, Alexander Gogos, Santiago Helbig, Lukas R. H. Gerken, Anna L. Neuer, Vera M. Kissling, Michal Krupinski, Mohammad Alinezhadfar, Rowena Crockett, Nico Kummer, Erik M. Mayr, Dieter Süss, Hans J. Hug, Inge K. Herrmann   +14 more
wiley   +1 more source

Metastatic Intraparotid Balloon Cell Melanoma: A Diagnostic Challenge. [PDF]

Head Neck Pathol
McKinney RA, Baumann KB, Foss RD.
europepmc   +1 more source