Results 151 to 160 of about 20,124 (297)

Multimodal Imaging Reveals Cerebral Microcirculation Dynamics and Mechanisms in Mouse Central Nervous System After Intranasal Infection With Recombinant Pseudorabies Virus

open access: yesAdvanced Science, EarlyView.
Multi‐modality imaging strategy applied to PRV‐induced central nervous system infection enables dynamic visualization of cerebrovascular dysfunction, including hyperemia, hypoperfusion, and vascular remodeling. These changes are linked to microglial activation and impaired angiogenesis, providing mechanistic insight into PRV neuropathogenesis and ...
Shuting Ling   +13 more
wiley   +1 more source

WolbachiaInfection and Expression of Cytoplasmic Incompatibility inArmigeres subalbatus(Diptera: Culicidae) [PDF]

open access: bronze, 2000
Wanwisa Jamnongluk   +3 more
openalex   +1 more source

SP3 and DEP1 Orchestrate Panicle Architecture by Jointly Regulating APO2 Expression in Rice

open access: yesAdvanced Science, EarlyView.
The transcription factor SP3 enhances inflorescence meristem activity and interacts with the cysteine‐rich domain of DEP1. This interaction alters DEP1's subcellular localization between the plasma membrane and nucleus, and suppresses SP3‐mediated transcriptional activation of APO2.
Yuexin Liu   +11 more
wiley   +1 more source

WITHIN-SPECIES DIVERSITY OF WOLBACHIA-INDUCED CYTOPLASMIC INCOMPATIBILITY IN HAPLODIPLOID INSECTS [PDF]

open access: bronze, 2001
Fabrice Vavre   +5 more
openalex   +1 more source

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

open access: yesAdvanced Science, EarlyView.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan   +16 more
wiley   +1 more source

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

open access: yesAdvanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou   +27 more
wiley   +1 more source

High‐Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline

open access: yesAdvanced Science, EarlyView.
This review highlights emerging state‐of‐the‐art high‐throughput strategies for optimising lipid nanoparticle formulation. By integrating combinatorial design, characterization, in vitro/in vivo screening, automation, and machine learning into a closed‐loop framework, it provides a roadmap to streamline discovery and accelerate the translation of ...
Lois Lam   +3 more
wiley   +1 more source

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