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Prolyl Oligopeptidase From Leishmania infantum: Biochemical Characterization and Involvement in Macrophage Infection

open access: yesFrontiers in Microbiology, 2020
Leishmania infantum is a flagellated protozoan and one of the main causative agents of visceral leishmaniasis. This disease usually affects the human reticuloendothelial system, can cause death and available therapies may lead to serious side effects ...
Camila Lasse   +16 more
doaj   +1 more source

Structural insights into the mechanism of archaellar rotational switching

open access: yesNature Communications, 2022
Signal transduction via phosphorylated CheY is conserved in bacteria and archaea. In this study, the authors employ structural biochemistry combined with cell biology to delineate the mechanism of CheY recognition by the adaptor protein CheF.
Florian Altegoer   +10 more
doaj   +1 more source

Library-independent source tracking of fecal contamination in selected stations and tributaries of Laguna Lake, Philippines

open access: yesJournal of Water and Health, 2021
Laguna Lake is the largest inland freshwater body in the Philippines. Although it is classified to be usable for agricultural and recreational purposes by the country's Department of Environment and Natural Resources (DENR), studies looking at lake ...
Joseth Jermaine M. Abello   +6 more
doaj   +1 more source

The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron sequestration and melanization

open access: yesmBio
Facultative endosymbiotic bacteria, such as Wolbachia and Spiroplasma species, are commonly found in association with insects and can dramatically alter their host physiology.
Alexandra Hrdina   +4 more
doaj   +1 more source

Intertwined Dysregulation of Ribosomal Proteins and Immune Response Delineates SARS-CoV-2 Vaccination Breakthroughs

open access: yesMicrobiology Spectrum, 2023
Globally, COVID-19 vaccines have emerged as a boon, especially during the severe pandemic phases to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, saving millions of lives.
Ranjeet Maurya   +7 more
doaj   +1 more source

Genetic variability in the sdrD gene in Staphylococcus aureus from healthy nasal carriers

open access: yesBMC Microbiology, 2018
Background Staphylococcus aureus cell wall anchored Serine Aspartate repeat containing protein D (SdrD) is a member of the microbial surface component recognising adhesive matrix molecules (MSCRAMMs).
Clement Ajayi   +5 more
doaj   +1 more source

Proteomic Mapping of Multifunctional Complexes Within Triatomine Saliva

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Triatomines are hematophagous insects that transmit Trypanosoma cruzi, the etiological agent of Chagas disease. This neglected tropical disease represents a global health issue as it is spreading worldwide.
Paula Beatriz Santiago   +8 more
doaj   +1 more source

Culturing periprosthetic tissue in BacT/Alert® Virtuo blood culture system leads to improved and faster detection of prosthetic joint infections

open access: yesBMC Infectious Diseases, 2019
Background Blood culture bottles (BCBs) provide a semiautomated method for culturing periprosthetic tissue specimens. A study evaluating BCBs for culturing clinical samples other than body fluids is needed before implementation into clinical practice ...
Adriana Sanabria   +5 more
doaj   +1 more source

Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite

open access: yesMolecular Systems Biology, 2020
Mutually exclusive expression of the var multigene family is key to immune evasion and pathogenesis in Plasmodium falciparum, but few factors have been shown to play a direct role.
Jessica M Bryant   +8 more
doaj   +1 more source

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