Results 11 to 20 of about 3,883,661 (304)
Hologenomics: Systems-Level Host Biology [PDF]
mSystems, 2018 The hologenome concept of evolution is a hypothesis explaining host evolution in the context of the host microbiomes. As a hypothesis, it needs to be evaluated, especially with respect to the extent of fidelity of transgenerational coassociation of host ...
Kevin R. Theis
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Systems biology of host–microbe metabolomics [PDF]
WIREs Systems Biology and Medicine, 2015 The human gut microbiota performs essential functions for host and well‐being, but has also been linked to a variety of disease states, e.g., obesity and type 2 diabetes. The mammalian body fluid and tissue metabolomes are greatly influenced by the microbiota, with many health‐relevant metabolites being considered ‘mammalian ...
HEINKEN, Almut Katrin, THIELE, Ines
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Host-aware synthetic biology [PDF]
Current Opinion in Systems Biology, 2019 Abstract Unnatural gene expression imposes a load on engineered microorganisms which decreases their growth and subsequent production yields, a phenomenon known as burden. In the last decade, the field of synthetic biology has made progress on the development of biomolecular feedback control systems and other approaches that can improve the growth of
Boo, A, Ellis, T, Stan, G
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Diagnostics, 2021 Isothermal techniques with lateral flow detection have emerged as a point of care (POC) technique for malaria, a major parasitic disease in tropical countries such as India.
Supriya Sharma +8 more
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The role of the host—Neutrophil biology
Periodontology 2000, 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of ...
Iain L. C. Chapple +4 more
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Malaria Journal, 2023 Background Drug resistance is a serious impediment to efficient control and elimination of malaria in endemic areas. Methods This study aimed at analysing the genetic profile of molecular drug resistance in Plasmodium falciparum and Plasmodium vivax ...
Loick P. Kojom Foko +5 more
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The spectrum of clinical biomarkers in severe malaria and new avenues for exploration
Virulence, 2022 Globally, malaria is a public health concern, with severe malaria (SM) contributing a major share of the disease burden in malaria endemic countries. In this context, identification and validation of SM biomarkers are essential in clinical practice. Some
Loick Pradel Kojom Foko +6 more
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Pathophysiology of Cerebral Malaria: Implications of MSCs as A Regenerative Medicinal Tool
Bioengineering, 2022 The severe form of malaria, i.e., cerebral malaria caused by Plasmodium falciparum, is a complex neurological syndrome. Surviving persons have a risk of behavioral difficulties, cognitive disorders, and epilepsy.
Amrendra Chaudhary +3 more
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CD4+ICOS+Foxp3+: a sub-population of regulatory T cells contribute to malaria pathogenesis
Malaria Journal, 2022 Background Regulatory T cells are known to play a key role to counter balance the protective immune response and immune mediated pathology. However, the role of naturally occurring regulatory cells CD4+CD25+Foxp3 + in malaria infection during the disease
Rubika Chauhan +5 more
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International Journal of Infectious Diseases, 2023 Intro: Chemical insecticides in the form of IRS (Indoor Residual Sprays) and LLITNs (Long Lasting Insecticide Treated Nets) comprise current malaria vector control strategies.
J. Kumar +3 more
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