Results 41 to 50 of about 608,192 (264)

Detection of the infective Plasmodium falciparum gametocytes by RT-qPCR assay from a malaria-endemic region of Northeastern India

Frontiers in Tropical Diseases
IntroductionThe diagnosis of infectious reservoirs in malaria (gametocytes) is necessary, especially in low-density infections and asymptomatic malaria patients. The gametocyte stage is a surrogate marker for infection of P. falciparum malaria in healthy
Ram Das, Kapil Vashisht, Lokesh Kori, Kuldeep Singh, Gaurav Kumar, Izazul Hasan, Jugal Gam, Kailash C. Pandey   +7 more
doaj   +1 more source

High-level integration of murine intestinal transcriptomics data highlights the importance of the complement system in mucosal homeostasis

BMC Genomics, 2019
Background The mammalian intestine is a complex biological system that exhibits functional plasticity in its response to diverse stimuli to maintain homeostasis.
Nirupama Benis, Jerry M. Wells, Mari A. Smits, Soumya Kanti Kar, Bart van der Hee, Vitor A. P. Martins dos Santos, Maria Suarez-Diez, Dirkjan Schokker   +7 more
doaj   +1 more source

Cell biology at the host–microbe interface

Molecular Biology of the Cell, 2014
Talks at the “Cell Biology at the Host–Microbe Interface” Minisymposium highlighted mechanisms used by viral, bacterial, and eukaryotic pathogens to hijack host-cell functions and establish a replicative niche. Manipulation of membrane dynamics Nihal Altan-Bonnet (National Institutes of Health) described positive-sense RNA enteroviruses that ...
Troemel, Emily, Valdivia, Raphael H.
openaire   +2 more sources

Unraveling dual feeding associated molecular complexity of salivary glands in the mosquito Anopheles culicifacies

Biology Open, 2015
Mosquito salivary glands are well known to facilitate meal acquisition, however the fundamental question on how adult female salivary gland manages molecular responses during sugar versus blood meal uptake remains unanswered.
Punita Sharma, Swati Sharma, Ashwani Kumar Mishra, Tina Thomas, Tanwee Das De, Suman Lata Rohilla, Namita Singh, Kailash C. Pandey, Neena Valecha, Rajnikant Dixit   +9 more
doaj   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior, Luiz Claudio Barreto Silva Neto, Fabiano Kenji Haraguchi, Letícia Batista de Azevedo, Marcelo Brenner Nascimento Carlini, Raphael Manhães Pessanha, Mariana Rabello Laignier, Wesley Rocha Grippa, Tania Mara Lopes Bitti Bortolini, Gláucia Zouain‐Figueiredo, Regina Aparecida Garcia de Lima, Liliana Vasquez   +11 more
wiley   +1 more source

The chemical biology of coronavirus host–cell interactions

RSC Chemical Biology, 2021
Chemical biology strategies can play important roles in studying the complexity of SARS-CoV-2–host interactions at molecular level detail.
Suprama Datta, Erik C. Hett, Kalpit A. Vora, Daria J. Hazuda, Rob C. Oslund, Olugbeminiyi O. Fadeyi, Andrew Emili   +6 more
openaire   +3 more sources

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Prolyl Oligopeptidase From Leishmania infantum: Biochemical Characterization and Involvement in Macrophage Infection

Frontiers in Microbiology, 2020
Leishmania infantum is a flagellated protozoan and one of the main causative agents of visceral leishmaniasis. This disease usually affects the human reticuloendothelial system, can cause death and available therapies may lead to serious side effects ...
Camila Lasse, Clênia S. Azevedo, Clênia S. Azevedo, Carla N. de Araújo, Carla N. de Araújo, Flávia N. Motta, Flávia N. Motta, Milene A. Andrade, Milene A. Andrade, Amanda Pereira Rocha, Iracyara Sampaio, Sébastien Charneau, Marc Gèze, Marc Gèze, Philippe Grellier, Jaime M. Santana, Izabela M. D. Bastos   +16 more
doaj   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source