Results 61 to 70 of about 1,352,426 (310)

Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model [PDF]

, 2008
The transgenomic metabolic effects of exposure to either Lactobacillus paracasei or Lactobacillus rhamnosus probiotics have been measured and mapped in humanized extended genome mice (germ-free mice colonized with human baby flora).
Allison C, Blum S, Cummings JH, Donaldson RM, Elaine Holmes, Fan TW, Francois‐Pierre J Martin, Fuller R, Ikram‐ul H, Ivan K S Yap, Jeremy K Nicholson, John C Lindon, Laurent B Fay, Macfarlane GT, Norbert Sprenger, Per Lek, Peter van Bladeren, Serge Rezzi, Sunil Kochhar, Torbjörn Lundstedt, Yulan Wang, Zeisel SH, Ziad Ramadan   +22 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into the mechanism of archaellar rotational switching

Nature Communications, 2022
Signal transduction via phosphorylated CheY is conserved in bacteria and archaea. In this study, the authors employ structural biochemistry combined with cell biology to delineate the mechanism of CheY recognition by the adaptor protein CheF.
Florian Altegoer, Tessa E. F. Quax, Paul Weiland, Phillip Nußbaum, Pietro I. Giammarinaro, Megha Patro, Zhengqun Li, Dieter Oesterhelt, Martin Grininger, Sonja-Verena Albers, Gert Bange   +10 more
doaj   +1 more source

Library-independent source tracking of fecal contamination in selected stations and tributaries of Laguna Lake, Philippines

Journal of Water and Health, 2021
Laguna Lake is the largest inland freshwater body in the Philippines. Although it is classified to be usable for agricultural and recreational purposes by the country's Department of Environment and Natural Resources (DENR), studies looking at lake ...
Joseth Jermaine M. Abello, Gicelle T. Malajacan, Kevin L. Labrador, Mae Ashley G. Nacario, Luiza H. Galarion, Marie Christine M. Obusan, Windell L. Rivera   +6 more
doaj   +1 more source

Integration of plastids with their hosts: Lessons learned from dinoflagellates. [PDF]

, 2015
After their endosymbiotic acquisition, plastids become intimately connected with the biology of their host. For example, genes essential for plastid function may be relocated from the genomes of plastids to the host nucleus, and pathways may evolve ...
Dorrell, Richard G, Howe, Christopher J
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Livestock abundance predicts vampire bat demography, immune profiles, and bacterial infection risk [PDF]

, 2018
Human activities create novel food resources that can alter wildlife–pathogen interactions. If resources amplify or dampen, pathogen transmission probably depends on both host ecology and pathogen biology, but studies that measure responses to ...
Altizer, Sonia, Becker, Daniel, Bentz, Alexandra B., Camus, Melinda S., Carrera, Jorge E., Chizhikov, Vladimir E., Czirjak, Gabor A., Fenton, M. Brock, Gilbert, Amy T., Navara, Kristen J., Recuenco, Sergio E., Simmons, Nancy B., Streicker, Daniel, Volokhov, Dmitriy V.   +13 more
core   +3 more sources

Cell biology at the host–microbe interface

Molecular Biology of the Cell, 2014
Talks at the “Cell Biology at the Host–Microbe Interface” Minisymposium highlighted mechanisms used by viral, bacterial, and eukaryotic pathogens to hijack host-cell functions and establish a replicative niche. Manipulation of membrane dynamics Nihal Altan-Bonnet (National Institutes of Health) described positive-sense RNA enteroviruses that ...
Troemel, Emily, Valdivia, Raphael H.
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Intertwined Dysregulation of Ribosomal Proteins and Immune Response Delineates SARS-CoV-2 Vaccination Breakthroughs

Microbiology Spectrum, 2023
Globally, COVID-19 vaccines have emerged as a boon, especially during the severe pandemic phases to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, saving millions of lives.
Ranjeet Maurya, Uzma Shamim, Pallavi Mishra, Aparna Swaminathan, Aakarshan Raina, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey   +7 more
doaj   +1 more source