Results 61 to 70 of about 652,566 (312)

Parasitic influences on the host genome using the molluscan model organism biomphalaria glabrata [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The freshwater snail Biomphalaria glabrata is an intermediate host for Schistosoma mansoni parasites, causing one of the most prevalent parasitic infections
Arican-Goktas, Halime Derya
core  

Dietary supply with polyunsaturated fatty acids and resulting maternal effects influence host -- parasite interactions [PDF]

, 2013
Interactions between hosts and parasites can be substantially modulated by host nutrition. Polyunsaturated fatty acids (PUFAs) are essential dietary nutrients; they are indispensable as structural components of cell membranes and as precursors for ...
Ebert, Dieter, Dieter Ebert, Dominik Martin-Creuzburg, Martin-Creuzburg, Dominik, Nina Schlotz, Schlotz, Nina   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Intertwined Dysregulation of Ribosomal Proteins and Immune Response Delineates SARS-CoV-2 Vaccination Breakthroughs

Microbiology Spectrum, 2023
Globally, COVID-19 vaccines have emerged as a boon, especially during the severe pandemic phases to control the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, saving millions of lives.
Ranjeet Maurya, Uzma Shamim, Pallavi Mishra, Aparna Swaminathan, Aakarshan Raina, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey   +7 more
doaj   +1 more source

Genomic evolution of the pathogenic Wolbachia strain, wMelPop [PDF]

, 2013
Most strains of the widespread endosymbiotic bacterium Wolbachia pipientis are benign or behave as reproductive parasites. The pathogenic strain wMelPop is a striking exception, however: it overreplicates in its insect hosts and causes severe life ...
McMeniman, Conor J., Sullivan, Mitchell J, Brownlie, Jeremy C, McGraw, Elizabeth A., Iturbe-Ormaeche, Inaki, McGraw, Elizabeth A, Popovici, Jean, Beatson, Scott A, Riegler, Markus (R14045), Sullivan, Mitchell J., Iturbe-Ormaetxe, Inaki, Woolfit, Megan, O'Neill, Scott L, Beatson, Scott A., Beatson, Scott, McMeniman, Conor, Walker, Thomas, Pavlides, Jennifer, Lane, Amanda, O'Neill, Scott L., Brownlie, Jeremy C., Sidhu, Manpreet, Rances, Edwige, McMeniman, Conor J, Seleznev, Andrei, Brownlie, Jeremy, Riegler, Markus, Wee, Bryan A, sullivan, Mitchell, O’Neill, Scott L., Wee, Bryan, McGraw, Elizabeth, O'Neill, Scott, Wee, Bryan A.   +33 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron sequestration and melanization

mBio
Facultative endosymbiotic bacteria, such as Wolbachia and Spiroplasma species, are commonly found in association with insects and can dramatically alter their host physiology.
Alexandra Hrdina, Marina Serra Canales, Aranzazu Arias-Rojas, Dagmar Frahm, Igor Iatsenko   +4 more
doaj   +1 more source

Systems biology and the host response to viral infection [PDF]

Nature Biotechnology, 2007
Will our increasing understanding of virus-host interactions translate into a new generation of antiviral therapeutics or steer us toward an expensive journey to nowhere?
Tan, Seng-Lai, Ganji, Gopinath, Paeper, Bryan, Proll, Sean, Katze, Michael G   +4 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

In Silico Approaches for the Identification of Aptamer Binding Interactions to Leptospira spp. Cell Surface Proteins

Tropical Medicine and Infectious Disease, 2023
Aptamers are nucleic acids that can bind with high affinity and specificity to a range of target molecules. However, their functionality relies on their secondary and tertiary structures such that the combination of nucleotides determines their three ...
Chembie A. Almazar, Marjo V. Mendoza, Windell L. Rivera   +2 more
doaj   +1 more source