Streptozotocin induced hyperglycemia in the axolotl
Developmental Dynamics, EarlyView.Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen +2 more
wiley +1 more source
Transcriptome Sequencing Reveals Novel Candidate Genes for Cardinium hertigii -Caused Cytoplasmic Incompatibility and Host-Cell Interaction [PDF]
, 2017 Evelyne Mann +5 more
openalex +1 more source
Amidine Syntheses from Classic to Contemporary for Medicinal Lead Compounds and Natural Products
European Journal of Organic Chemistry, EarlyView.A revolution is underway in the synthesis of amidines with new methods unlocking complex, highly substituted amidines or closely related derivatives such as N‐sulfonyl amidines. This review surveys recent advances in amidines and related compounds, including methods to install them and bioactive molecules prominently featuring the amidine functionality.
Wyatt R. Swift‐Ramirez +1 more
wiley +1 more source
Evolutionary Genetics of Cytoplasmic Incompatibility Genes cifA and cifB in Prophage WO of Wolbachia [PDF]
, 2018 Amelia R. I. Lindsey +5 more
openalex +1 more source
Critical Evaluation of Methods for the Identification of Aneugens
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun +8 more
wiley +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Epilepsia Open, EarlyView.Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Multi‐Energy Integrated Photocatalysis for Antitumor Therapy
Exploration, EarlyView.This comprehensive review summarizes recent advancements in piezo‐photocatalysts and photothermal‐photocatalysts for cancer therapy. It begins by outlining the principles of piezo‐photocatalysis and photothermal‐photocatalysis, followed by a discussion of various multi‐energy integrated photocatalysts designed for single‐, dual‐, triple‐, and tetra ...
Li Zhang +4 more
wiley +1 more source
Recombination, Truncation and Horizontal Transfer Shape the Diversity of Wolbachia-induced Cytoplasmic Incompatibility Patterns. [PDF]
Mol Biol EvolNamias A +11 more
europepmc +1 more source