Results 101 to 110 of about 39,037 (343)

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Non-coding RNA may be associated with cytoplasmic male sterility in Silene vulgaris

Journal of Experimental Botany, 2017
Highlight A comparison of mitochondrial transcript levels and RNA editing between females and hermaphrodites of Silene vulgaris suggests that mitochondrial non-coding RNA is putatively associated with cytoplasmic male sterility.
James D. Stone, Pavla Koloušková, Daniel B. Sloan, H. Štorchová   +3 more
semanticscholar   +1 more source

Dynein‐Dependent Endo‐Lysosomal Degradation Drives Lewy Body Disorders Accompanied by Aβ Pathology

Advanced Science, EarlyView.
This study investigates the impact of Aβ plaques on α‐synuclein (αSyn) pathologies in dementia with Lewy bodies (DLB). Co‐culturing primary neurons with AD mouse brain slices reveals impaired dynein‐dependent organelle trafficking, affecting αSyn degradation. Activating Rab7 restores this process, reducing αSyn inclusions.
Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Yuting Guan, Virginia Man‐Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu   +14 more
wiley   +1 more source

The Role of Non-Coding RNAs in Cytoplasmic Male Sterility in Flowering Plants

International Journal of Molecular Sciences, 2017
The interactions between mitochondria and nucleus substantially influence plant development, stress response and morphological features. The prominent example of a mitochondrial-nuclear interaction is cytoplasmic male sterility (CMS), when plants produce
H. Štorchová
semanticscholar   +1 more source

Natural Allelic Variations in IbCHYR1–IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato

Advanced Science, EarlyView.
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang, Zhuoru Dai, Xiaochen Zhang, Meiqi Shang, Xiaoru Gao, Ruiqi Ma, Limeng Zhao, Xiaoli Zhang, Qingchang Liu, Hong Zhai, Shaopei Gao, Ning Zhao, Qinghe Cao, Qiang Li, Shaozhen He   +14 more
wiley   +1 more source

sThe chimeric gene atp6c confers cytoplasmic male sterility in maize by impairing the assembly of mitochondrial ATP synthase complex.

Molecular Plant, 2022
Huili Yang, Yadong Xue, Bing Li, Yanan Lin, Haochuan Li, Zhanyong Guo, Wei-hua Li, Z. Fu, D. Ding, Jihua Tang   +9 more
semanticscholar   +1 more source

Morphological Structure and Transcriptome Comparison of the Cytoplasmic Male Sterility Line in Brassica napus (SaNa-1A) Derived from Somatic Hybridization and Its Maintainer Line SaNa-1B

Frontiers in Plant Science, 2016
SaNa-1A is a novel cytoplasmic male sterility (CMS) line in Brassica napus derived from progenies of somatic hybrids between B.napus and Sinapis alba, and SaNa-1B is the corresponding maintainer line.
K. Du, Qier Liu, Xinyue Wu, Jinjin Jiang, Jian Wu, Yujie Fang, Aimin Li, Youping Wang   +7 more
semanticscholar   +1 more source

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Male sterility of triticale lines generated through recombination of triticale and rye maintainers

Spanish Journal of Agricultural Research, 2014
The Triticum timopheevi cytoplasmic male sterility (cms) system in triticale (xTriticosecale Wittmack) suffers from a low frequency of maintainers and environmental instability of the male sterility. On the other hand, the Pampa cms system in rye (Secale
Tomasz Warzecha, Agnieszka Sutkowska, Halina Góral   +2 more
doaj   +1 more source

Comparative Analysis of the Cytology and Transcriptomes of the Cytoplasmic Male Sterility Line H276A and Its Maintainer Line H276B of Cotton (Gossypium barbadense L.)

International Journal of Molecular Sciences, 2017
In this study, the tetrad stage of microspore development in a new cotton (Gossypium barbadense L.) cytoplasmic male sterility (CMS) line, H276A, was identified using paraffin sections at the abortion stage.
Xiangjun Kong, Dongmei Liu, Xiaofang Liao, Jie Zheng, Y. Diao, Yiding Liu, Ruiyang Zhou   +6 more
semanticscholar   +1 more source