Results 51 to 60 of about 14,870 (257)

A Lightweight, 3D‐Printable, Low‐Cost, “One‐Click” Dorsal Skin Window for High‐Quality Long‐Term Multimodal Subcutaneous Tumor Imaging

Advanced Healthcare Materials, EarlyView.
An innovative, lightweight 3D‐printed skinfold chamber system is presented for long‐term intravital imaging. This affordable, biocompatible platform simplifies surgical implantation and allows high‐resolution, multimodal visualization of the tumor microenvironment for up to four weeks.
Iván Cortés Domínguez, Xabier Morales Urteaga, Maider Esparza, Lucía Grande, Ainhoa Urbiola, Cristina Ederra, Tomas Muñoz Santoro, Beatrice Pinci, Alvaro Teijeira, Carlos Ortiz de Solórzano   +9 more
wiley   +1 more source

Restorer-of-Fertility Mutations Recovered in Transposon-Active Lines of S Male-Sterile Maize

G3: Genes, Genomes, Genetics, 2018
Mitochondria execute key pathways of central metabolism and serve as cellular sensing and signaling entities, functions that depend upon interactions between mitochondrial and nuclear genetic systems.
Susan Gabay-Laughnan, A. Mark Settles, L. Curtis Hannah, Timothy G. Porch, Philip W. Becraft, Donald R. McCarty, Karen E. Koch, Liming Zhao, Terry L. Kamps, Karen C. Chamusco, Christine D. Chase   +10 more
doaj   +1 more source

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

DETERMINATION OF CYTOPLASMIC MALE STERILE FACTORS IN ONION PLANTS ( ALLIUM CEPA L.) OF VNIISSOK'S BREEDING

Овощи России, 2011
Molecular markers were used for screening of the onion plants of VNIISSOK's breeding for cytoplasmic male sterility. Allelic variations of the mitochondrial genes orfА501 and cob were reveled among studied onion samples.
T.P. Suprunova, A.N. Logunov, V.V. Logunova, A.F. Agafonov   +3 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Crearea şi utilizarea analogilor androsterili şi restauratori de fertilitate a polenului la porumbul timpuriu

Agricultural Science, 2019
The paper presents a generalization of the results of multiannual investigations concerning the reaction of early maize lines to M-type and C-type cytoplasmic male sterility (cms) and the development of male sterile analogues and pollen fertility ...
MUSTEAȚA Simion , BOROZAN Pantelimon , RUSU Ghenadie , SPÎNU Valentina   +3 more
doaj  

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui, Zhencong Chen, Guangyao Shan, Zhengyang Hu, Xing Jin, Jiaqi Liang, Yanjun Yi, Jiacheng Yin, Haochun Shi, Xifei Jiang, Junjie Xi, Zongwu Lin, Cheng Zhan, Fenghao Sun, Wei Jiang   +14 more
wiley   +1 more source

Advances in cytoplasmic male sterility phenotype and infertility mechanism

Guangxi Zhiwu
The presence of some specialized open reading frames(ORFs)within plant mitochondrial genomes can cause the failure of male gamete production or their abnormal fertilization, which is referred to as cytoplasmic male sterility(CMS).
WANG Xuesong1,2, ZOU Yi1, WANG Jie1, NIE Liyun1, WU Zhiqiang1*
doaj   +1 more source

Association of nad7a Gene with Cytoplasmic Male Sterility in Pigeonpea

The Plant Genome, 2015
Cytoplasmic male sterility (CMS) has been exploited in the commercial pigeonpea [ (L.) Millsp.] hybrid breeding system; however, the molecular mechanism behind this system is unknown.
Pallavi Sinha, K. B. Saxena, Rachit K. Saxena, Vikas K. Singh, V. Suryanarayana, C.V. Sameer Kumar, Mohan A.V.S. Katta, Aamir W. Khan, Rajeev K. Varshney   +8 more
doaj   +1 more source

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

Advanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang, Guanda Qiao, Honglin Tan, Colleen Russel, Baixuan Yang, Mengyang Jacky Li, Kexin Wang, Jiadi Xu, Chengyan Chu, Miroslaw Janowski, Tian‐Ming Fu, Piotr Walczak, Yajie Liang   +12 more
wiley   +1 more source