Results 71 to 80 of about 2,233,741 (284)

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Mitochondrially-targeted expression of a cytoplasmic male sterility-associated orf220 gene causes male sterility in Brassica juncea [PDF]

, 2010
Background The novel chimeric open reading frame (orf) resulting from the rearrangement of a mitochondrial genome is generally thought to be a causal factor in the occurrence of cytoplasmic male sterility (CMS).
Jinghua Yang, Xunyan Liu, Mingfang Zhang, Xiaodong Yang, Yang Xiaodong, Liu Xunyan, Yang Jinghua, Zhang Mingfang   +7 more
core   +2 more sources

Development of male sterile broccoli lines with raphanus sativus cytoplasm and assessment of their value for breeding purposes

Journal of Horticultural Research, 2013
The aim of this study was to obtain new broccoli lines with cytoplasmic male sterility trait for the development of the modern F1 hybrids. CDT70 cauliflower line obtained in the Research Institute of Horticulture, formerly Research Institute of Vegetable
Kamiński Piotr
doaj   +1 more source

Fertility restoration studies in short duration redgram (Cajanus cajan (L.) mill spp.) hybrids involving cgms system

Madras Agricultural Journal, 2008
Fertility restoration is a crucial requirement for successful hybrid synthesis using CGMS system in crops. This investigation was carried out with the objective to explore the extent of fertility restoration for various cytoplasmic sources across ...
N.Nadarajan, S. Ganesh Ram and K.Indira Petchiammal   +1 more
doaj   +1 more source

A possible origin for the sugar beet cytoplasmic male sterility source Owen

, 1989
The cytoplasmic male sterility source of sugar beet used for hybrid seed production is distinguished from the maintainer (O type) by the HindIII chloroplast DNA (ctDNA) restriction pattern.
A. Geny, J.-F. Bonavent, L. Bessone, A. Berville, J.-P. Denizot, C. Brian   +5 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Association of nad7a Gene with Cytoplasmic Male Sterility in Pigeonpea

The Plant Genome, 2015
Cytoplasmic male sterility (CMS) has been exploited in the commercial pigeonpea [ (L.) Millsp.] hybrid breeding system; however, the molecular mechanism behind this system is unknown.
Pallavi Sinha, K. B. Saxena, Rachit K. Saxena, Vikas K. Singh, V. Suryanarayana, C.V. Sameer Kumar, Mohan A.V.S. Katta, Aamir W. Khan, Rajeev K. Varshney   +8 more
doaj   +1 more source

Development of a cytoplasmic nuclear male-sterility system in pigeonpea using C. scarabaeoides (L.) Thouars [PDF]

, 2003
The phenomenon of heterosis has been successfully exploited for the genetic enhancement of yield in a number of cereal and horticultural crops. In pigeon pea, significant yield gains have also been demonstrated through genetic male sterility-based hybrid
Saxena, K B, Kumar, R V
core