Results 31 to 40 of about 22,744 (213)

Overcoming steroid resistance in T cell acute lymphoblastic leukemia [PDF]

, 2016
In a Perspective, Pieter Van Vlierberghe and Steven Goossens discuss Meijerink and colleagues' findings on steroid resistance in pediatric T cell acute lymphoblastic ...
Goossens, Steven, Van Vlierberghe, Pieter   +1 more
core   +3 more sources

Risk predictors of early recurrence in women with epithelial ovarian cancer in Lagos, Nigeria

The Pan African Medical Journal, 2020
INTRODUCTION: Epithelial ovarian cancer (EOC) is the most lethal gynaecological cancer with a recurrence rate as high as 85% after an initial treatment. However, there are currently no reliable means of predicting the risk of recurrence after first-line ...
Kehinde Sharafadeen Okunade, Imoleayo Elijah Adetuyi, Muisi Adenekan, Ephraim Ohazurike, Rose Ihuoma Anorlu   +4 more
doaj   +1 more source

Intraperitoneal chemotherapy for peritoneal metastases : an expert opinion

, 2020
Introduction: The rationale for intraperitoneal (IP) drug delivery for patients with peritoneal metastases (PM) is based on the pharmacokinetic advantage resulting from the peritoneal-plasma barrier, and on the potential to adequately treat small, poorly
Braet, Helena, Ceelen, Wim, Remaut, Katrien, Van Ramshorst, Gabrielle, Willaert, Wouter   +4 more
core   +1 more source

Early Investigations and Recent Advances in Intraperitoneal Immunotherapy for Peritoneal Metastasis. [PDF]

, 2018
Peritoneal metastasis (PM) is an advanced stage malignancy largely refractory to modern therapy. Intraperitoneal (IP) immunotherapy offers a novel approach for the control of regional disease of the peritoneal cavity by breaking immune tolerance.
Bowne, Wilbur B., Katz, Steven C., Khalili, Marian, Morano, William F., Richard, Scott D., Thadi, Anusha   +5 more
core   +2 more sources

Preoperative predictors for residual tumor after surgery in patients with ovarian carcinoma [PDF]

, 2008
Objectives: Suboptimal debulking (>1 cm residual tumor) results in poor survival rates for patients with an advanced stage of ovarian cancer. The purpose of this study was to develop a prediction model, based on simple preoperative parameters, for ...
A. Baalbergen, A.C. Ansink, Aletti GD, Aure JC, Bast, Bell R, Bozkurt N, Brockbank EC, C.G. Gerestein, C.W. Burger, Chi DS, Cooper BC, D. de Jong, Eisenkop SM, Eisenkop SM, Eltabbakh GH, Ferrero A, G.S. Kooi, Gatta G, Gemer O, Grover S, Hacker NF, Herrmann, Hoskins WJ, International Federation of Gynecology and Obstetrics, Jacobs I, Lawton FG, Le T, M.E.L. van der Burg, M.J. Eijkemans, Mamtora H, Menon U, Mor V, Morice P, Obermair A, Obermair A, Park JY, Park TW, Parker D, Petterson F, Rector, S. Lie Fong, Saygili U, Schneider D, van der Burg ME, Van Houwelingen JC, Varras M, Vergote I, Vergote I, Vergote IB, Warwick J, Yuce K   +51 more
core   +7 more sources

3D laparoscopy as a tertiary cytoreductive (TCR) surgery in infiltrating ureter recurrent epithelial ovarian cancer – case report and a mini-review of the literature

Menopause Review, 2018
The paper describes a case of a 61-year-old woman with recurrent epithelial ovarian cancer infiltrating the ureter treated with 3D laparoscopy as a tertiary cytoreductive surgery (TCR).
Tomasz Szopiński, Igal Mor, Krzysztof Okoń, Włodzimierz Baranowski, Małgorzata Jerzak   +4 more
doaj   +1 more source

Survival Outcomes and Prognostic Analysis Following Greater Cytoreductive Radiotherapy in Patients With Metastatic Prostate Cancer

Frontiers in Oncology, 2020
Purpose: To assess the survival outcomes of patients with metastatic prostate cancer (mPCa) who undergo greater cytoreductive radiotherapy in a real-world clinical practice and determine their prognostic factors.Methods: We performed a retrospective ...
Zitong Zhang, Min Wei, Lixin Mai, Yonghong Li, Jianhua Wu, Hong Huang, Sijuan Huang, Maosheng Lin, Xiaobo Jiang, Fangjian Zhou, Mengzhong Liu, Yang Liu, Liru He   +12 more
doaj   +1 more source

Does the Performance of Splenectomy as Part of Cytoreductive Surgery Carry a Worse Prognosis Than in Patients Not Receiving Splenectomy? A Propensity Score Analysis and Review of the Literature

Journal of Investigative Surgery, 2022
Background & Objectives Ultra-radical (UR) procedures, including splenectomy, are utilized to increase complete cytoreduction rates during Cytoreductive Surgery (CRS) performed with the aim of complete macroscopic clearance of disease.
James Davies, Viren Asher, Anish Bali, Summi Abdul, Andrew Phillips   +4 more
doaj   +1 more source

Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity. [PDF]

, 2017
BackgroundProdrug-activator gene therapy with Toca 511, a tumor-selective retroviral replicating vector (RRV) encoding yeast cytosine deaminase, is being evaluated in recurrent high-grade glioma patients.
Gruber, Harry E, Hacke, Katrin, Hiraoka, Kei, Huang, Tiffany T, Inagaki, Akihito, Jolly, Douglas J, Kamijima, Shuichi, Kasahara, Noriyuki, Kato, Yuki, Kruse, Carol A, Matsumoto, Hiroshi, Mitchell, Leah A, Ostertag, Derek, Robbins, Joan M, Takahashi, Masamichi   +14 more
core   +1 more source

Role for targeted resection in the multidisciplinary treatment of metastatic gastrointestinal stromal tumor [PDF]

, 2019
The management of advanced gastrointestinal stromal tumors (GISTs) has evolved in the modern era due to the discovery of c-kit mutations and the development of tyrosine kinase inhibitors (TKIs).
Feizpour, Cyrus, Kays, Joshua K., Kim, Bradford J., Koniaris, Leonidas G., Milgrom, Daniel P.   +4 more
core   +1 more source