Results 51 to 60 of about 7,054 (204)

Impact of fluid and haemodynamic management in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy on postoperative outcomes – A systematic review

Indian Journal of Anaesthesia, 2023
Background and Aims: Cytoreduction surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is an extensive surgery associated with significant fluid shift and blood loss.
Sohan Lal Solanki, Indubala Maurya, Jyoti Sharma   +2 more
doaj   +1 more source

Dynamic Profiling of Circulating Tumor Cells and MYC/PTEN Alterations in Prostate Cancer Patients Undergoing Radical Prostatectomy in Amazon Population

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed malignancy among men and the sixth leading cause of cancer‐related mortality worldwide. Radical prostatectomy remains the standard treatment for localized disease; however, approximately one‐third of patients develop biochemical recurrence within 10 years. Although prostate‐specific
Juliana Ramos Chaves, Rommel Mario Rodriguez Burbano, Amanda de Nazaré Cohen‐Paes, Diego Di Felipe Ávila Alcântara, Ana Paula Borges de Souza, Maria Janete Nahum Gomes, Sérgio Augusto Antunes Ramos, André Salim Khayat   +7 more
wiley   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source

Does hyperthermic intraoperative chemotherapy lead to improved outcomes in patients with ovarian cancer? A single center cohort study in 111 consecutive patients

Patient Safety in Surgery, 2012
Background For recurrent disease or primary therapy of advanced ovarian cancer, cytoreductive surgery (CRS) followed by adjuvant chemotherapy is a therapeutic option.
Warschkow Rene, Tarantino Ignazio, Lange Jochen, Müller Sascha A, Schmied Bruno M, Zünd Michael, Steffen Thomas   +6 more
doaj   +1 more source

Spectral CT in peritoneal carcinomatosis from ovarian cancer: a tool for differential diagnosis of small nodules?

European Radiology Experimental, 2022
The detection of peritoneal carcinomatosis in patients with ovarian cancer is crucial to establish the correct therapeutic planning (debulking surgery versus neoadjuvant chemotherapy).
Giada Zorzetto, Andrea Coppola, Valeria Molinelli, Maria Gloria Angeretti, Jvan Casarin, Federico Fontana, Filippo Piacentino, Giulio Carcano, Fabio Ghezzi, Massimo Venturini   +9 more
doaj   +1 more source

Advances in the Treatment of Colorectal Cancer with Peritoneal Metastases: A Focus on Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

The Ewha Medical Journal, 2023
In stage IV colorectal cancer (CRC), peritoneal metastasis is associated with a poor prognosis. Hyperthermic intraperitoneal chemotherapy (HIPEC) after cytoreductive surgery (CRS) is an effective treatment option ...
Youngbae Jeon, Eun Jung Park
doaj   +1 more source

Salvage cytoreductive surgery for patients with recurrent endometrial cancer: a retrospective study [PDF]

, 2014
BACKGROUND: Salvage cytoreductive surgery (SCR) has been shown to improve the survival of cancer patients. This study aimed to determine the survival benefits of SCR for recurrent endometrial cancer in Chinese population.
Boer Shan, Daren Shi, Huaying Wang, Yulan Ren   +3 more
core   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Adjuvant hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with colon cancer at high risk of peritoneal carcinomatosis; the COLOPEC randomized multicentre trial [PDF]

, 2015
Background: The peritoneum is the second most common site of recurrence in colorectal cancer. Early detection of peritoneal carcinomatosis (PC) by imaging is difficult.
Aalbers, A.G.J. (Arend), Bemelman, W.A. (Willem), Boerma, D. (Djamila), Bremers, A.J.A. (Andreas), Burger, J.W.A. (Jacobus), Buskens, C.J. (Christianne), Dijkgraaf, M.G.W. (Marcel), Evers, P. (Pauline), Grevenstein, H.M.U. (Helma) van, Hemmer, P.H.J. (Patrick H.J.), Hingh, I.H.J.T. (Ignace) de, Klaver, C.E.L. (Charlotte), Lammers, L.A. (Laureen), Leeuwen, B.L. (B.) van, Meijerink, W.J.H.J. (Jeroen), Musters, G.D. (Gijsbert), Nienhuijs, S.W. (Simon), Pon, J. (Jolien), Punt, C.J.A. (Cornelis), Radema, S.A. (Sandra A.), Ramshorst, B. (Bert) van, Snaebjornsson, P., Tanis, P.J. (Pieter), te Velde, E.A. (Elisabeth A.), Tuynman, J.B., van der Bilt, J.D.W. (Jarmila D.W.), van Ginkel, R.J. (Robert J.), Verwaal, V.J. (Vic J.), Wiezer, M.J. (Marinus), Wilt, J.H.W. (Johannes) de   +29 more
core   +4 more sources

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, Volume 158, Issue 9, Page 2440-2451, 1 May 2026.
What's new? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source