Results 61 to 70 of about 7,054 (204)

Assessing the Safety of Craniotomy for Resection of Primary Central Nervous System Lymphoma: A Nationwide Inpatient Sample Analysis

Frontiers in Neurology, 2017
BackgroundUnlike many other central nervous system (CNS) tumors, the surgical management of primary central nervous system lymphomas (PCNSL) is traditionally limited by diagnostic biopsy.
Jonathan Yun, Jingyan Yang, Michael Cloney, Amol Mehta, Suprit Singh, Fabio Massaiti Iwamoto, Alfred I. Neugut, Alfred I. Neugut, Alfred I. Neugut, Adam M. Sonabend   +9 more
doaj   +1 more source

Protocol of a retrospective, multicentre observational study on hyperthermic intrathoracic chemotherapy in Germany

BMJ Open, 2020
Introduction Objective of the ‘German hyperthermic intrathoracic chemotherapy (HITOC) study’ is to evaluate the HITOC as additional treatment after surgical cytoreduction for malignant pleural tumours.
Gunnar Huppertz, Hauke Winter, Rudolf Hatz, Till Markowiak, Florian Zeman, Hans-Stefan Hofmann, Michael Ried, Martin Eichhorn, Laura Klotz, Julia Zimmermann, Julia Kovacs, Bernward Passlick, Severin Schmid, Mohamed Hassan   +13 more
doaj   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

Pure abscopal effect in a patient with advanced uterine carcinosarcoma

Radiology Case Reports, 2023
The abscopal effect is a rare phenomenon, in which tumor shrinkage in the nonirradiated metastatic region is observed after radiotherapy. Certainly, this response is sometimes reported with the combined use of immune-checkpoint inhibitors, but a pure ...
Kazuhiro Okamoto, MD, Kotaro Yoshio, MD, PhD, Shinsuke Shirakawa, MD, Kyohei Irie, MD, Naoyuki Ida, MD, PhD, Hirofumi Matsuoka, MD, PhD, Junko Haraga, MD, PhD, Chikako Ogawa, MD, PhD, Keiichiro Nakamura, MD, PhD, Shoji Nagao, MD, PhD, Hisashi Masuyama, MD, PhD   +10 more
doaj   +1 more source

Oncologic Outcomes of Cytoreductive Radical Prostatectomy in Patients With Synchronous Metastatic Castration‐Sensitive Prostate Cancer: A Retrospective Analysis

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Objectives Local therapy for metastatic castration‐sensitive prostate cancer (mCSPC) remains controversial. This study aimed to assess the feasibility, safety, and oncologic outcomes of cytoreductive radical prostatectomy (cRP) in patients with synchronous mCSPC, with a particular focus on pathological findings.
Kento Morozumi, Kenji Numahata, Masaaki Oikawa, Masato Konno, Hiroki Kusumoto, Kuromoto Akito, Yuki Katsumata, Masahiko Sato, Yasuhiro Kaiho   +8 more
wiley   +1 more source

HE4 in the differential diagnosis of ovarian masses [PDF]

, 2015
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela, ANGELONI, Antonio, Flavia Longo, MANGANARO, Lucia, PORPORA, Maria Grazia, Teresa Granato   +5 more
core   +1 more source

Advanced Ovarian Dysgerminoma With Supraclavicular Lymph Node Metastasis and Peritoneal Carcinomatosis: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Ovarian dysgerminoma is a rare, highly chemo‐sensitive germ cell tumor usually presenting early. We report a FIGO stage IVB case with supraclavicular lymph node metastasis and peritoneal carcinomatosis in a 31‐year‐old woman. Diagnosis was based on classical histopathology.
Bishal Khaniya, Sushant Shah, Dhiraj Adhikari, Abhaya Acharya, Aashish Poudel, Suresh Gautam   +5 more
wiley   +1 more source

Transaortic removal of a large primary sarcoma from the left ventricle assisted by strategic partial resection and endoscopic guidance: a case report

Journal of Cardiothoracic Surgery
Background Surgical resection remains the mainstay of treatment for cardiac sarcoma, a rare but lethal disease. Achieving complete removal of a large-sized left ventricular sarcoma remains a challenge even with various surgical approaches that have been ...
Jae-Sung Choi, Jeongwon Kim, Se Jin Oh, You Jung Ok, Yong Won Seong, Hyeon Jong Moon   +5 more
doaj   +1 more source

Goal-directed fluid therapy using transoesophageal echocardiographic inferior venacaval index in patients with low left ventricular ejection fraction undergoing major cytoreductive surgery: A clinical trial

Saudi Journal of Anaesthesia, 2020
Background and Aims: This study aims to trans oesophageal echo cardiographically (TOE) measure inferior venacava diameter (IVCD) during inspiration and expiration in poor left ventricular ejection fraction (LVEF) patients undergoing cytoreductive ...
Shagun Bhatia Shah, Ajay Kumar Bhargava, Uma Hariharan, Chamound Rai Jain, Anita Kulkarni, Namrata Gupta   +5 more
doaj   +1 more source

Successful Interstitial HDR Brachytherapy for Nasal Skin SCC in Xeroderma Pigmentosum: An Eight‐Year Follow‐Up Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT High‐dose‐rate interstitial brachytherapy may provide durable local control with acceptable cosmetic outcomes in carefully selected patients with xeroderma pigmentosum and cutaneous squamous cell carcinoma. This long‐term follow‐up case questions the absolute contraindication of radiotherapy in XP and underscores the importance of ...
Pouya Saraei, Vita Derakhshandeh, Ali Bagheri   +2 more
wiley   +1 more source