Results 61 to 70 of about 3,130,322 (229)

Surgical Techniques for Diaphragmatic Resection During Cytoreduction in Advanced or Recurrent Ovarian Carcinoma: A Systematic Review and Meta-analysis

open access: yes, 2016
Optimal cytoreduction is one the main factors improving survival outcomes in patients affected by ovarian cancer (OC). It is estimated that approximately 40% of OC patients have gross disease located on the diaphragm.
DI DONATO, VIOLANTE   +9 more
core   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

open access: yesPhotochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore   +6 more
wiley   +1 more source

Does hyperthermic intraoperative chemotherapy lead to improved outcomes in patients with ovarian cancer? A single center cohort study in 111 consecutive patients

open access: yesPatient Safety in Surgery, 2012
Background For recurrent disease or primary therapy of advanced ovarian cancer, cytoreductive surgery (CRS) followed by adjuvant chemotherapy is a therapeutic option.
Warschkow Rene   +6 more
doaj   +1 more source

Cytoreduction for Colorectal Metastases: Liver, Lung, Peritoneum, Lymph Nodes, Bone, Brain. When Does it Palliate, Prolong Survival, and Potentially Cure?

open access: yesCurrent problems in surgery, 2018
Colorectal cancer commonly metastasizes. The liver is the most frequent site of metastases and dominates the length of survival for this disease. As surgical and systemic therapies have become accepted and now are proven to be potentially curative, other
C. Stewart   +8 more
semanticscholar   +1 more source

Stage IV Ovarian Cancer Is Not Uniformly Lethal: Two Subgroups With Stage II‐Like Outcomes Identified in Large Retrospective Cohorts

open access: yesCancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background The International Federation of Gynecology and Obstetrics (FIGO) staging system for advanced ovarian cancer has remained largely static since 2014, with stage IV subdivided into IVA and IVB without further stratification. Emerging evidence suggests substantial prognostic heterogeneity within stage IV, yet large‐scale validation ...
Cheng Fang, Jundong Li, Qiaqia Li
wiley   +1 more source

Effective cytoreduction can be achieved in patients with numerous neuroendocrine tumor liver metastases (NETLMs),

open access: yesSurgery, 2018
Background: Cytoreductive surgery for neuroendocrine tumor liver metastases improves survival and symptomatic control. However, the feasibility of adequate cytoreduction in patients with many liver metastases remains uncertain.
Aaron T Scott   +6 more
semanticscholar   +1 more source

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 9, Page 2244-2261, 1 November 2026.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko   +31 more
wiley   +1 more source

Assessing the Safety of Craniotomy for Resection of Primary Central Nervous System Lymphoma: A Nationwide Inpatient Sample Analysis

open access: yesFrontiers in Neurology, 2017
BackgroundUnlike many other central nervous system (CNS) tumors, the surgical management of primary central nervous system lymphomas (PCNSL) is traditionally limited by diagnostic biopsy.
Jonathan Yun   +9 more
doaj   +1 more source

Advances in the Treatment of Colorectal Cancer with Peritoneal Metastases: A Focus on Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

open access: yesThe Ewha Medical Journal, 2023
In stage IV colorectal cancer (CRC), peritoneal metastasis is associated with a poor prognosis. Hyperthermic intraperitoneal chemotherapy (HIPEC) after cytoreductive surgery (CRS) is an effective treatment option ...
Youngbae Jeon, Eun Jung Park
doaj   +1 more source

Estimating Individualized Survival Benefit of Consolidative Metastasis‐Directed Radiotherapy Following Chemoimmunotherapy in Nasopharyngeal Carcinoma With Exclusive Distant Metastasis

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This study integrates target trial emulation and causal machine learning to individualize consolidative metastasis‐directed radiotherapy (MDRT) for exclusively distant metastatic nasopharyngeal carcinoma. Using a multicenter cohort of 1083 patients, we confirmed overall MDRT efficacy via a cloning–censoring–weighting approach.
Xuguang Wang   +13 more
wiley   +1 more source

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