Results 81 to 90 of about 7,054 (204)

Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo, Cuilan Yun, Yuemei Zhang, Xu Yang, Huiqin Liu   +4 more
wiley   +1 more source

A Case Illustrating Challenges: Early‐Onset Signet Ring Cell Rectal Carcinoma With Fulminant Peritoneal Progression

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Signet ring cell carcinoma (SRCC) of the rectum is a rare histologic subtype and is often associated with aggressive behavior and poor outcomes, particularly in young patients. We report a 19‐year‐old male who presented with acute intestinal obstruction and was diagnosed with rectal SRCC, radiologically staged as cT2N1bM0, acknowledging the ...
Shivraj Sharma, Madhav Raj Karki, Aron Neupane, Shristi Gupta, Dikshya Pokhrel, Kshitiz Parajuli, Nikhil Agarwal   +6 more
wiley   +1 more source

An update of peritonectomy procedures used in cytoreductive surgery for peritoneal malignancy

International Journal of Hyperthermia, 2019
Background: Complete cytoreduction is acknowledged to be an effective way to achieve macroscopic tumor clearance for a variety of tumors confined to the peritoneal cavity.
Frédéric Mercier, Faheez Mohamed, Jean-Baptiste Cazauran, Vahan Kepenekian, Delphine Vaudoyer, Eddy Cotte, Olivier Glehen, Guillaume Passot   +7 more
doaj   +1 more source

GEICO (Spanish Group for Investigation on Ovarian Cancer) treatment guidelines in ovarian cancer 2012 [PDF]

, 2013
In 2006, under the auspices of The Spanish Research Group for Ovarian Cancer (Spanish initials GEICO), the first “Treatment Guidelines in Ovarian Cancer” were developed and then published in Clinical and Translational Oncology by Poveda Velasco et al ...
A Bois du, A Bois du, A Bois du, A Bois du, A Fagotti, A Gentry-Maharaj, A Poveda, A Poveda Velasco, A Rosenthal, A Umar, A. Cervantes, A. De Juan, A. González Martín, A. Poveda Velasco, A. Redondo, AJ Gonzalez-Martin, American College of Obstetricians and Gynecologists, AR Khan, B Trimbos, BA Goff, Biomarkers Definitions Working Group, BJ Monk, BM Norquist, C Aghajanian, C Fotopoulou, C. Mendiola, Cancer Genome Atlas Research Network, CG Przybycin, D Vicus, DG Evans, DK Armstrong, DK Armstrong, DS Alberts, DS Chi, DT Wheeler, E Leblanc, E Pujade-Lauraine, EL Eisenhauer, G Singer, GC Stuart, GJ Rustin, HFA Vasen, I Shih, I Vergote, I. Bover, I. Romero, J Bell, J Boyd, J Pfisterer, J Pfisterer, J Prat, J. A. López-Guerrero, J. M. Del Campo, J. Palacios, JB Trimbos, JB Trimbos, JD Seidman, JP Neijt, JR Nagell Jr, JS Berek, JS Ng, KC Wiegand, KK Shih, KL Bolton, KM Lin, KP Pennington, KR Kim, M Adams, M Kaur, M Markman, M Markman, M. J. Rubio, M. Jurado, MA Bookman, MA Merritt, ME Robson, MJ Piccart, MK Parmar, N Bharwani, N Colombo, N Colombo, N Katsumata, N Sato, P Morice, PJ Hoskins, R Leonard, RA Burger, RC Young, RE Bristow, RF Ozols, RF Ozols, RH Verheijen, RH Young, RJ Kurman, RT Zon, S Guerriero, S Pecorelli, S Pignata, SM Domchek, SS Buys, T Gorp Van, T Thigpen, TJ Perren, TR Rebbeck, U Menon, W Bocker, WP McGuire, Y. García   +107 more
core   +1 more source

Tumour‐targeted fluorescence‐guided surgery in gastrointestinal cancer: A systematic review of preclinical and clinical research

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Tumour‐targeted fluorescence‐guided surgery (Ttfgs) enhances intraoperative precision in gastrointestinal cancer treatment. Translation of (Ttfgs) into clinical practice is limited by heterogeneity, regulatory hurdles, biomarker variability and absence of phase III trials.
Aaya Darai, Evie H. M. Graus, Femke J. A. van der Stroom, Mark Rijpkema, Alexander Vahrmeijer, Denise E. Hilling, Johannes H. W. De Wilt, Merlijn Hutteman   +7 more
wiley   +1 more source

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6)

BMC Cancer, 2019
Background Upfront cytoreductive surgery with HIPEC (CRS-HIPEC) is the standard treatment for isolated resectable colorectal peritoneal metastases (PM) in the Netherlands.
Koen P. Rovers, Checca Bakkers, Geert A. A. M. Simkens, Jacobus W. A. Burger, Simon W. Nienhuijs, Geert-Jan M. Creemers, Anna M. J. Thijs, Alexandra R. M. Brandt-Kerkhof, Eva V. E. Madsen, Ninos Ayez, Nadine L. de Boer, Esther van Meerten, Jurriaan B. Tuynman, Miranda Kusters, Nina R. Sluiter, Henk M. W. Verheul, Hans J. van der Vliet, Marinus J. Wiezer, Djamila Boerma, Emma C. E. Wassenaar, Maartje Los, Cornelis B. Hunting, Arend G. J. Aalbers, Niels F. M. Kok, Koert F. D. Kuhlmann, Henk Boot, Myriam Chalabi, Schelto Kruijff, Lukas B. Been, Robert J. van Ginkel, Derk Jan A. de Groot, Rudolf S. N. Fehrmann, Johannes H. W. de Wilt, Andreas J. A. Bremers, Philip R. de Reuver, Sandra A. Radema, Karin H. Herbschleb, Wilhelmina M. U. van Grevenstein, Arjen J. Witkamp, Miriam Koopman, Nadia Haj Mohammad, Eino B. van Duyn, Walter J. B. Mastboom, Leonie J. M. Mekenkamp, Joost Nederend, Max J. Lahaye, Petur Snaebjornsson, Cornelis Verhoef, Hanneke W. M. van Laarhoven, Aeilko H. Zwinderman, Jeanette M. Bouma, Onno Kranenburg, Iris van ‘t Erve, Remond J. A. Fijneman, Marcel G. W. Dijkgraaf, Patrick H. J. Hemmer, Cornelis J. A. Punt, Pieter J. Tanis, Ignace H. J. T. de Hingh, Dutch Peritoneal Oncology Group (DPOG), Dutch Colorectal Cancer Group (DCCG)   +60 more
doaj   +1 more source

Feasibility and Safety of Pressurized Intraperitoneal Aerosol Chemotherapy for Peritoneal Carcinomatosis: A Retrospective Cohort Study. [PDF]

, 2017
Background. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been introduced as a novel repeatable treatment for peritoneal carcinomatosis.
Demartines, N., Grass, F., Hahnloser, D., Hübner, M., Mathevet, P., Teixeira Farinha, H., Wolfer, A.   +6 more
core   +3 more sources

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, Volume 2, Issue 1, Page 89-105, March 2026.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

Venous thromboembolic events following cytoreductive surgery for lower gastrointestinal neoplasia

Surgery in Practice and Science
Introduction: Cytoreductive surgery (CRS) and intraperitoneal chemotherapy (IPC) represent a high-risk for venous thromboembolism (VTE) due to malignancy, prolonged surgery and immobility.
Mina Guirgis, Simon Keelan, Philip McEntee, Margaret Han, Paul Moroz   +4 more
doaj   +1 more source

Which patient is going to benefit from surgical cytoreduction with intraperitoneal chemotherapy (for manifest peritoneal metastases)?

Current Issues in Pharmacy and Medical Sciences, 2017
The gastric cancer with peritoneal metastases still represents a serious problem in the oncological surgery, whereas the peritoneal metastases arising from colorectal cancer can be successfully treated using a multimodal therapy concept consisting of ...
Blaj Sebastian, Piso Pompiliu
doaj   +1 more source