Results 81 to 90 of about 3,130,322 (229)

The Role of Tumor Debulking Surgery in Improving Survival of Patients with Head and Neck Cancer: A Systematic Review

Current Oncology
Background/Objectives: Data on the value of tumor debulking surgery are scarce. We aimed to examine whether tumor debulking surgery followed by non-surgical treatment (cases) improves survival compared to non-surgical treatment alone (controls) in ...
Aris I. Giotakis, Evangelos Tagkalos, Matthias Santer, Daniel Dejaco, Benedikt Hofauer   +4 more
doaj   +1 more source

Advanced Primary Cervical Carcinosarcoma With Ovarian and Peritoneal Metastases in a Premenopausal Woman: A Rare Case Report From Northern Tanzania

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Cervical carcinosarcoma (CCS), also known as malignant mixed Müllerian tumor (MMMT) of the cervix, is an exceptionally rare and aggressive biphasic neoplasm composed of both epithelial and mesenchymal malignant components. Due to its rarity, optimal management strategies are not well established, particularly in low‐resource settings.
John Lugata, Gidion Kategugwa, Kimberly R. Sladek, Abitalis Mayengela, Kenneth Bagandanshwa, Baraka Shao, Edrick Elias, Joseph Mlay, Bariki Mchome, Eusebious Maro, Alex Mremi, Fredrick Mbise   +11 more
wiley   +1 more source

Ultra-radical surgery versus standard-radical surgery for the primary cytoreduction of advanced epithelial ovarian cancer; long-term tertiary center experiences.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
OBJECTIVE To compare overall survival (OS) and morbidity outcomes in patients with advanced epithelial ovarian/tubal/peritoneal cancer undergoing standard-radical (SR) and ultra-radical (UR) surgical procedures based on NICE classification.
Alperen Aksan, N. Boran, Ayse Sinem Duru Coteli, Yaprak Ustun   +3 more
semanticscholar   +1 more source

Desmoplastic Small Round Cell Tumor: Long-Term Complications After Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy

Annals of Surgical Oncology, 2019
Background Desmoplastic small round cell tumor (DSRCT) is a rare intra-abdominal soft tissue sarcoma affecting adolescents and young adults. Cytoreduction, hyperthermic intraperitoneal chemotherapy (CRS/HIPEC), and adjuvant radiotherapy may improve local
Zachary E. Stiles, A. Murphy, D. Anghelescu, Christina-Lin Brown, A. Davidoff, P. Dickson, E. Glazer, Michael W. Bishop, W. Furman, A. Pappo, John T. Jr Lucas, J. Deneve   +11 more
semanticscholar   +1 more source

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan, Ke Tang, Linglong Wang, Qin Tian, Mingwei Zheng, Cheng Qian, Limei Liu   +6 more
wiley   +1 more source

Extensive surgical cytoreduction and intraoperative hyperthermic intraperitoneal chemotherapy in patients with pseudomyxoma peritonei [PDF]

, 2020
Background: Pseudomyxoma peritonei remains a fatal disease. However, extensive surgical cytoreduction combined with intraoperative heated intraperitoneal chemotherapy (HIPEC) has recently emerged as a new treatment modality, which might improve survival.
G W Van Slooten, Dr F A N Zoetmulder, A J Witkamp, F Van Coevorden, F A N Zoetmulder, E De Bree, M M Kaag   +6 more
core  

KRAS Mutations in Cancers: From Undruggable Dilemma to Precision Medicine

MedComm, Volume 7, Issue 10, October 2026.
KRAS‐mutant cancers are therapeutically shaped by both allele identity and tumor context. Direct KRAS inhibition has achieved the greatest clinical success in KRAS G12C‐mutant NSCLC, whereas colorectal cancer often requires EGFR cotargeting and pancreatic cancer remains constrained by stromal and metabolic barriers. Shared resistance mechanisms include
Jiaying Cai, Yimin Wu, Xing Jia, Li Yang, Wenjun Yang, Weishan Lu, Zhiye Huang, Yang Pan, Zixuan Fei, Junnan Ru, Jiazheng Zhao, Jue Shen, Taobo Luo, Da Chen, Haihong Yu, Haihan Deng, Jian Zeng, Wenmei Jiang, Leilei Wu   +18 more
wiley   +1 more source

Venous thromboembolic events following cytoreductive surgery for lower gastrointestinal neoplasia

Surgery in Practice and Science
Introduction: Cytoreductive surgery (CRS) and intraperitoneal chemotherapy (IPC) represent a high-risk for venous thromboembolism (VTE) due to malignancy, prolonged surgery and immobility.
Mina Guirgis, Simon Keelan, Philip McEntee, Margaret Han, Paul Moroz   +4 more
doaj   +1 more source

Differentiating high‐ and low‐grade serous ovarian carcinoma using radiomics: a pilot study

Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 4, Page 559-570, October 2026.
ABSTRACT Objective To identify ultrasound‐based radiomics features capable of distinguishing between high‐grade serous ovarian carcinomas (HGSC) and invasive low‐grade serous ovarian carcinomas (LGSC), and to develop machine‐learning models that include radiomics features to discriminate between the two.
F. Ciccarone, G. Zinicola, E. H. Tran, G. Baldassari, E. Boccia, C. Nero, F. Moro, T. Pasciuto, G. Scambia, G. Ferrandina, A. Fagotti, A. C. Testa, D. Lorusso, Collaborators, F. Borella, F. Buonomo, R. Fruscio, F. Pozzati, R. Mancari   +18 more
wiley   +1 more source

Perioperative Factors Affecting Successful On-table Tracheal Extubation after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: A Retrospective Study

Journal of Onco-Anaesthesiology and Perioperative Medicine
Background and Aims: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is an advanced, complex and curative surgical procedure in primary and secondary peritoneal cancers.
Suparna Mitra Barman, Rudranil Nandi, Sudipta Kundu, Neha Desai, Sudipta Mukherjee, Jyotsna Goswami   +5 more
doaj   +1 more source