Results 341 to 350 of about 279,378 (380)
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Adenine base editors catalyze cytosine conversions in human cells
Nature Biotechnology, 2019Heon Seok Kim +2 more
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Biochemistry, 1993
Previous spectroscopic studies demonstrated that the oligodeoxynucleotide d(CGC G3 GCG) undergoes a reversible cation-dependent transition between Watson-Crick (WC) hairpin and parallel-stranded "G-DNA" quadruplex structures [Hardin, C.C., Watson, T., Corregan, M., & Bailey, C. (1992) Biochemistry 31, 833-841].
Charles C. Hardin +3 more
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Previous spectroscopic studies demonstrated that the oligodeoxynucleotide d(CGC G3 GCG) undergoes a reversible cation-dependent transition between Watson-Crick (WC) hairpin and parallel-stranded "G-DNA" quadruplex structures [Hardin, C.C., Watson, T., Corregan, M., & Bailey, C. (1992) Biochemistry 31, 833-841].
Charles C. Hardin +3 more
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On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs
Cell, 1983In recent years 5methylcytosine residues in DNA have been implicated to have an important role in the control of eucaryotic gene expression (see Razin and Riggs, Science 210,604-610,198O). Consequently, there has been much interest in cytosine analogs such as 5azacytosine (5.azaC) and 5-fluorocytosine (5.fluoro-C), which, when incorporated into DNA ...
Daniel V. Santi +2 more
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How to Distinguish Methyl-Cytosine from Cytosine with High Fidelity [PDF]
Journal of Molecular Biology, 2012 Methylation of cytosines in the DNA is central to the epigenetic code. The patterns along the DNA formed by these chemical marks instruct the cell which proteins to express and their faithful maintenance after replication are vital to the organism's life.
Caterina Bianca Neve Aurora Bianchi +2 more
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Methods for detection of cytosine and thymine modifications in DNA
Nature Reviews Chemistry, 2018Mark Berney, Joanna F Mcgouran
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Tautomeric exchange in cytosine
Biochemical and Biophysical Research Communications, 1971Abstract It has long been noted that the H 5 proton of cytosine and its related derivatives exhibits unusually broad resonances in the pmr spectrum under certain conditions of temperature and solution pD. We have examined this phenomenon as a function of temperature, solution pD as well as the external magnetic field, and have shown that the line ...
J. H. Prestegard +2 more
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Solvolyses of Cytosine and Cytidine
Journal of Pharmaceutical Sciences, 1972It has been confirmed by UV spectrophotometry and TLC that cytosine and cytidine deaminate to uracil and uridine, respectively, at all pH values. These products slowly degrade further in strongly alkaline solutions. Cytidine also undergoes a parallel degradation in strongly alkaline solutions to a nonchromophoric compound, which can be assigned to a ...
Edward R. Garrett, Josef Tsau
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Nucleic Acids Research, 2015 The function of RNA is subtly modulated by post-transcriptional modifications. Here, we report an important crosstalk in the covalent modification of two classes of RNAs. We demonstrate that yeast Kre33 and human NAT10 are RNA cytosine acetyltransferases
Sunny Sharma, Denis L J Lafontaine
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Enzymology of cytosine arabinoside
Medical and Pediatric Oncology, 1982The enzymes responsible for the metabolism of Ara-C and its metabolites in human cells are described. The relevance of the properties of those enzymes to the action of Ara-C is discussed.
Yung-Chi Cheng, Robert L. Capizzi
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The Full Cytosine‐Cytosine Base Paring: Self‐Assembly and Crystal Structure
Chemistry – A European Journal, 2023AbstractThe synthesis of self‐assembly systems that can mimic partial biological behaviours require ingenious and delicate design. For decades, scientists are committed to exploring new base pairing patterns using hydrogen bonds directed self‐assembly of nucleotides.
Zhongkui Li +6 more
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