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Functions and Malfunctions of Mammalian DNA-Cytosine Deaminases
Chemical Reviews, 2016 Kang Chen, Ashok S Bhagwat
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Determination of 5-methyl-cytosine and cytosine in tumor DNA of cancer patients
ELECTROPHORESIS, 2005The determination of the relative methylation in DNA tumor samples, in order to evaluate the activity of some anti-cancer drugs, has become a very important issue in the clinical field. Capillary electrophoresis (CE) applications in this area have been done previously but no good separation for model samples or tumor samples has been reported.
Alma Luisa Revilla Vázquez +3 more
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ChemInform Abstract: Ozonolyses of Cytosines and Guanine.
ChemInform, 1991AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hiroshige Muramatsu +3 more
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Synthesis and structure of cytosine dichloride cuprate: direct bonding of copper to cytosine
Acta Crystallographica Section C Crystal Structure Communications, 1990Dichlorobis(cytosine)copper(II), [CuCl2-(C4H5N3O)2], Mr = 356.65, monoclinic, P2(1)/n, a = 8.399 (2), b = 13.773 (2), c = 10.775 (2) A, beta = 90.8 (2) degrees, V = 1246.3 (9) A3, Z = 4, Dx = 1.901 Mg m-3, lambda (Mo K alpha) = 0.7107 A, mu = 2.195 mm-1, F(000) = 716, T = 298 K, R = 0.032, wR = 0.037 for 2313 reflections greater than 2 sigma(F).
E. Palacios, D. Tran Qui
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Cytosine modifications in myeloid malignancies
Pharmacology & Therapeutics, 2015Aberrant DNA methylation is a hallmark of many cancers, including the myeloid malignancies acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). The discovery of TET-mediated demethylation of 5-methylcytosine (5mC) and technological advancements in next-generation sequencing have permitted the examination of other cytosine modifications ...
Maria E. Figueroa, Kristen Meldi
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Selective modification of cytosines in oligodeoxyribonucleotides
Bioconjugate Chemistry, 1992A single deoxycytidine residing in an oligodeoxyribonucleotide which also contains 5-methyldeoxycytidines can be selectively derivatized with various alkylamines by sodium bisulfite-catalyzed transamination. Selective transamination results because 5-methylcytosine, unlike cytosine, does not form a bisulfite adduct.
Paul S. Miller, Cynthia D. Cushman
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The Fine Structure of Cytosine
Australian Journal of Chemistry, 1962The ionization constants and ultraviolet spectra of cytosine, of its appropriately methylated derivatives, and of related compounds are used to indicate that its pre- dominant tautomeric form in aqueous solution is 4-amino-1,2-dihydro-2-oxopyrimidine.
DJ Brown, M Lyall
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Inorganica Chimica Acta, 1980
Abstract The preparation is described of complexes of cytosine (= L) with the divalent metal ions manganese to zinc. The chloro- and bromo-complexes generally have the stoichiometry ML2X2, whereas iodides, nitrates and perchlorates commonly form ML4X2·O or 2H2O.
Margaret Goodgame, Keith W. Johns
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Abstract The preparation is described of complexes of cytosine (= L) with the divalent metal ions manganese to zinc. The chloro- and bromo-complexes generally have the stoichiometry ML2X2, whereas iodides, nitrates and perchlorates commonly form ML4X2·O or 2H2O.
Margaret Goodgame, Keith W. Johns
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The cytosine—fluoride interaction
Spectrochimica Acta Part A: Molecular Spectroscopy, 1986Abstract The DNA nucleobase cytosine forms a strong easily polarizable hydrogen bond with F − . Infrared and NMR characteristics for the hydrogen bond are reported. The hydrogen bond appears to be able to exist in both hydrated and anhydrous forms.
Elizabeth M. Goodman, James H. Clark
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