Results 171 to 180 of about 12,300,004 (314)

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

Synthesis and Cytotoxic Activity Study of Conjugates of N-Acyl Derivatives of 3,5-Bis(benzylidene)-4-piperidones and Phenothiazine. [PDF]

Int J Mol Sci
Yudaev P, Aleksandrova Y, Shagina I, Artyushin O, Sharova E, Rodionov A, Neganova M, Brel V.   +7 more
europepmc   +1 more source

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Protein Fraction and Derived Peptides from <i>Amaranthus hypochondriacus</i>: A Preliminary In Vitro Study of Cytotoxic Activity in Cancer Cell Lines. [PDF]

Int J Mol Sci
Reséndiz-Otero F, Valadez-Vega C, Velázquez-Morales BP, Bernardino-Nicanor A, Velasco-Azorsa R, Betanzos-Cabrera G, Salazar-Campos A, Muñoz-Pérez VM, Morales-González JA.   +8 more
europepmc   +1 more source

Tivantinib (ARQ197) Displays Cytotoxic Activity That Is Independent of Its Ability to Bind MET

Clinical Cancer Research, 2013
C. Basilico, Selma Pennacchietti, E. Vigna, C. Chiriaco, S. Arena, A. Bardelli, D. Valdembri, G. Serini, P. Michieli   +8 more
semanticscholar   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

Advanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han, Shuvra Mondal, Sungkeun Han, Chan‐Hwi Eom, Venkata Ramesh Naganaboina, Suk‐Won Hwang   +5 more
wiley   +1 more source

In Vitro Characterization of Internalization Pathways and Cytotoxic Activity of Anti-HSPG2 Antibody-Drug Conjugates in MDA-MB-231-LM2 Cells. [PDF]

Cancers (Basel)
Shao Z, Morelli L, Blass BE, Efimov A, Panyam J.   +4 more
europepmc   +1 more source

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

Advanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang, Daniel P. Mayer, Prabhat K. Purbey, Yingzi Liu, Kindra Kelly‐Scumpia, Clara Kang, Natalie Tsubamoto, Dhriti Bolangadi, Iqra Arshad, Charisse Ng, Maksim V. Plikus, Dino Di Carlo, Jason S. Weinstein, Philip O. Scumpia   +13 more
wiley   +1 more source

Evaluation of the antimicrobial and cytotoxic activity of nerolidol encapsulated in a nanoliposome system. [PDF]

Front Vet Sci
Mezzasalma N, Spadini C, Righi F, Simoni M, Lamberti G, Barba AA, Greco D, Merelli A, Bosio L, Cupola A, Schiano E, Taddei S, Cabassi CS.   +12 more
europepmc   +1 more source

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

Advanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia, Constantine Vogiatzis, Alejandra Planells‐Devesa, Emre Dikici, Caroline Vieira Maluf, Vasudev Vivekanand Nayak, Paulo G. Coelho, Lukasz Witek, Alicia Bilbao, Daniel Bilbao, Prasoon Mohan, Sapna Deo, Sylvia Daunert   +12 more
wiley   +1 more source