Results 111 to 120 of about 23,522 (211)

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Longitudinal T-Cell Phenotypic Dynamics During Sustained Antiretroviral Therapy in People With HIV. [PDF]

Open Forum Infect Dis
Vanpouille C, Wells A, DeGruttola V, Lynch M, Zhang X, Tu XM, Chaillon A, Woodworth B, Gaitan N, Rawlings SA, Landay A, Weber KM, Scully EP, Karn J, Gianella S.   +14 more
europepmc   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, EarlyView.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

LIMD2 is associated with an exhausted CD8⁺ T cell state linked to ICI response in clear cell renal cell carcinoma. [PDF]

Sci Rep
Zhang J, Peng Q, Xiang X, Liu F, Jiang X, Nie H, Bi X, Pan T, Li K, Chen P, Yuan S, Chen S.   +11 more
europepmc   +1 more source

Remote‐Controllable Immune‐Priming Spot Formation Via Nanocomplexed Hydrogel‐Assisted Histotripsy: Immunoasis

Advanced Materials, EarlyView.
A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim, Wonseok Choi, Yurim Kim, Hyeongmin Kim, Gu Won Jeong, Hyewon Park, Inchan Youn, Yoon Park, Sungmin Han, Young‐Min Kim   +9 more
wiley   +1 more source

Epitope-level analysis of cross-reactive human HLA antibodies against genetically modified swine leukocyte antigens in xenotransplantation. [PDF]

Front Immunol
Cho SI, Yan JJ, Kim BS, Ko N, Shim J, Kim H, Oh EJ.   +6 more
europepmc   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

NK cell function down regulated by HMGB2 through ANGPT1/PI3K/AKT pathway and its effect on esophageal squamous carcinoma cells. [PDF]

Front Immunol
Yin X, Cai H, Zhang A, Zheng W, Zhao J, Ma J.   +5 more
europepmc   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

The combination of LILRB4-targeting NK cell engagers and cGAS-STING agonists enhances the anti-multiple myeloma immune activity of NK cells. [PDF]

PLoS One
Li M, Zhao Y, Zhao L, Chen X, Kang J, Tong A, Yang C, Wang P, Yang M, Wang K, Gao J, Li Y, Fu X.   +12 more
europepmc   +1 more source