Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals.
Kay Choong See
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A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo
Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Hannah E. Scales +10 more
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Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease [PDF]
Background Endothelial cell (EC) dysfunction is a frequent feature in patients with end-stage renal disease (ESRD). The aim of this study was to generate human induced pluripotent stem cells, differentiate ECs (hiPSC-ECs) from patients with ESRD, and ...
Kyoung Woon Kim +7 more
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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males [PDF]
Purpose: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the zona pellucida. Synthesis of human anti-PCSK4 might be
Dahril +3 more
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Assessment of intracanal medications cytotoxicity on L929 fibroblast cells
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias +6 more
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Morphologic Spectrum of Undetermined Causes of Hemoptysis- A Pathologist's Role
Objective: Hemoptysis is the expectoration of blood or blood-streaked sputum from the tracheobronchial tree. The etiology may derive from nonneoplastic conditions such as infections, chronic pulmonary diseases, and vasculitis or neoplastic causes ...
Nidhya GANESAN, Umamaheswari GURUSAMY
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The intersection of COVID-19 and autoimmunity: What is our current understanding?
Viral infections have historically had a complex relationship with autoimmune diseases. For patients with preexisting autoimmune disorders, often complicated by immunosuppressive therapies, there are numerous potential effects of COVID-19, a disease of ...
Nicole Eve Winchester +2 more
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Topology and adenocarcinoma cell localization dataset on the labyrinthin diapeutic biomarker
Objective The discovery and characterization of tumor associated antigens is increasingly important to advance the field of immuno-oncology. In this regard, labyrinthin has been implicated as a neoantigen found on the cell surface of adenocarcinomas ...
Ankit Sharma +3 more
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Evolving Immunologic Perspectives in Chronic Inflammatory Demyelinating Polyneuropathy
Yusuf A Rajabally,1,2 Shahram Attarian,3,4 Emilien Delmont3,4 1Inflammatory Neuropathy Clinic, University Hospitals Birmingham, Birmingham, UK; 2Aston Medical School, Aston University, Birmingham, UK; 3Reference Centre for Neuromuscular Diseases and ALS,
Rajabally YA, Attarian S, Delmont E
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Introduction: Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder affecting the nasal and paranasal sinus mucosa for more than 12 weeks, with a significant global health impact.
Juan Pablo Alzate-Granados +5 more
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