The Ambiguity in Immunology [PDF]
In the present article, we discuss the various ambiguous aspects of the immune system that render this complex biological network so highly flexible and able to defend the host from different external invaders. This ambiguity stems mainly from the property of the immune system to be both protective and harmful.
BARNABA, Vincenzo +2 more
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Immunologic incompetence of immunologically runted animals [PDF]
1. Adult (A x C57Bl/1)F1 hybrids regularly show runt disease when injected with adult spleen cells from A strain donors. This also occurs when A strain spleen cells are administered to adult C3H mice made tolerant of A strain tissue in the neonatal period. 2.
Blaese, R M, Martinez, C, Good, R A
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IMMUNOLOGY OF TUBERCULOSIS [PDF]
MTB ranks as the first worldwide pathogen latently infecting one third of the population and the second leading cause of death from a single infectious agent, after the human immunodeficiency virus (HIV). The development of vigorous and apparently appropriate immune response upon infection with M.tuberculosis in humans and experimental animals conflict
Bozzano F, Marras F, DE MARIA, ANDREA
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Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals.
Kay Choong See
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A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo
Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Hannah E. Scales +10 more
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Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease [PDF]
Background Endothelial cell (EC) dysfunction is a frequent feature in patients with end-stage renal disease (ESRD). The aim of this study was to generate human induced pluripotent stem cells, differentiate ECs (hiPSC-ECs) from patients with ESRD, and ...
Kyoung Woon Kim +7 more
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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males [PDF]
Purpose: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the zona pellucida. Synthesis of human anti-PCSK4 might be
Dahril +3 more
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Assessment of intracanal medications cytotoxicity on L929 fibroblast cells
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias +6 more
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Regenerative immunology: the immunological reaction to biomaterials [PDF]
Regenerative medicine promises to meet two of the most urgent needs of modern organ transplantation, namely immunosuppression-free transplantation and an inexhaustible source of organs. Ideally, bioengineered organs would be manufactured from a patient's own biomaterials-both cells and the supporting scaffolding materials in which cells would be ...
Paolo Cravedi +7 more
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Immunological Genome Project and systems immunology [PDF]
Immunological studies of single proteins in a single cell type have been complemented in recent years by larger studies, enabled by emerging high-throughput technologies. This trend has recently been exemplified by the discovery of gene networks controlling regulatory and effector αβ T cell subset development and human hematopoiesis.
Tal, Shay, Joonsoo, Kang
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