Results 21 to 30 of about 22,112 (211)

Magnetofection potentiates gene delivery to cultured endothelial cells [PDF]

, 2003
Modification of cellular functions by overexpression of genes is increasingly practised for research of signalling pathways, but restricted by limitations of low efficiency. We investigated whether the novel technique of magnetofection (MF) could enhance
Gloe, Torsten, Krötz, Florian, Plank, Christian, Pohl, Ulrich, Sohn, Hae-Young   +4 more
core   +1 more source

Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]

, 1980
Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Allen, H., Gething, M. J., Klenk, H. D., Koszinowski, Ulrich H., Waterfield, M. D.   +4 more
core   +2 more sources

The Biologic Response to Polyetheretherketone (PEEK) Wear Particles in Total Joint Replacement: A Systematic Review [PDF]

, 2016
Background: Polyetheretherketone (PEEK) and its composites are polymers resistant to fatigue strain, radiologically transparent, and have mechanical properties suitable for a range of orthopaedic applications.
Amstutz, Bladen, Holt, Ingram, Kabir, Latif, Matthews, Pace, Skinner, Wright   +9 more
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

In vitro culture with gemcitabine augments death receptor and NKG2D ligand expression on tumour cells [PDF]

, 2019
Much effort has been made to try to understand the relationship between chemotherapeutic treatment of cancer and the immune system. Whereas much of that focus has been on the direct effect of chemotherapy drugs on immune cells and the release of antigens
A Ashkenazi, A Cerwenka, A Hadji, A Orbach, AP Costa-Pereira, Baryshnikov AYu, C Fionda, H Cho, HA Elrod, I Viard-Leveugle, J Sträter, J Wu, JC Symes, K Yamamoto, L Boldrini, L Galligan, L Siena, M Christgen, M Mottolese, M Müller, M Todaro, M Villa-Morales, MA Park, ME Peter, N Gordon, O Micheau, PB Carvalho-Neto de, RW McGilvray, S Yang, V Almendro, WM Liu, Y Hirooka, Y Kimura   +32 more
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Efeitos citotóxicos e genotóxicos das ligas de solda de prata em ortodontia: revisão sistemática [PDF]

, 2015
Foi realizada uma revisão sistemática dos efeitos citotóxicos e genotóxicos das ligas de solda de prata em Ortodontia. Para tanto, foi efetuada uma busca sistemática nas bases de dados PubMed, EMBASE, Web of Science e Biblioteca Cochrane.
Garcia, Renato Dalla Porta
core  

Serotyping for homotransplantation V. Evaluation of a matching scheme [PDF]

, 1966
An attempt was made to determine whether 36 long-term kidney homograft recipients and their donors were compatible for 7 major leukocyte groups. It was found that 21 of these recipients were surviving 2 to 3 years in spite of incompatibility for 1 or 2 ...
Faris, TD, Herrmann, TJ, Marchioro, TL, Mickey, MR, Porter, KA, Starzl, TE, Terasaki, PI, Vredevoe, DL   +7 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source