Results 21 to 30 of about 3,061,339 (237)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
PSYNDEX Tests Review für FTF-K - FRANKFURTER TESTS FÜR FÜNFJÄHRIGE - KONZENTRATION
This is a PSYNDEX Tests Review of FTF-K - FRANKFURTER TESTS FÜR FÜNFJÄHRIGE - KONZENTRATION. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries. PSYNDEX Tests is
Raatz, Ulrich
core +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
PSYNDEX Tests Review für RCT (1) - READING COMPREHENSION TESTS 1
This is a PSYNDEX Tests Review of RCT (1) - READING COMPREHENSION TESTS 1. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Proekel, Gerhard
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
PSYNDEX Tests Review für ST-SM - Sporttest: Sportmotorische Tests für Mädchen
This is a PSYNDEX Tests Review of ST-SM - Sporttest: Sportmotorische Tests für Mädchen. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Waschler, Gerhard
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
PSYNDEX Tests Review für LKT 5-6 - Lesekompetenz-Tests
This is a PSYNDEX Tests Review of LKT 5-6 - Lesekompetenz-Tests. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Mayer, Anne-Kathrin
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
PSYNDEX Tests Review für FAT - Flugangst-Tests
This is a PSYNDEX Tests Review of FAT - Flugangst-Tests. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Weiderer, Monika
core +1 more source

