Results 51 to 60 of about 364,305 (138)
Pesquisa Brasileira em Odontopediatria e Clínica IntegradaObjective: To compare the cytotoxicity of polymethyl methacrylate dentures fabricated through compression molded and injection molded processing techniques.
Hemashree Emayavarman +7 more
doaj
Gap Junctions: The Claymore for Cancerous Cells [PDF]
BioImpacts, 2011, 1(2), 113-119, 2011 Introduction: Gap junctions play an important role in the cell proliferation in mammalian cells as well as carcinogenesis. However, there are controversial issues about their role in cancer pathogenesis. This study was designed to evaluate genotoxicity and cytotoxicity of Carbenoxolone (CBX) as a prototype of inter-cellular gap junction blocker in MCF7
arxiv
Modelling Immunological Memory [PDF]
In Silico Immunology, 83-108, 2006, 2010 Accurate immunological models offer the possibility of performing highthroughput experiments in silico that can predict, or at least suggest, in vivo phenomena. In this chapter, we compare various models of immunological memory. We first validate an experimental immunological simulator, developed by the authors, by simulating several theories of ...
arxiv
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
Journal for ImmunoTherapy of CancerBackground The antitumor activity of natural killer (NK) cells can be enhanced by specific targeting with therapeutic antibodies that trigger antibody-dependent cell-mediated cytotoxicity (ADCC) or by genetic engineering to express chimeric antigen ...
J. Eitler +18 more
semanticscholar +1 more source
Blood, 1982 Chronic lymphocytic leukemia of T-cell origin (T-CLL), a rare variant of CLL, appears to be a clonal proliferation of mature T cells of one of several subsets.
F. Pandolfi +8 more
semanticscholar +1 more source
Computational Inference Methods for HIV-1 Selective Sweeps Shaped by Early Cytotoxic T-Lymphocyte Response [PDF]
arXiv, 2012 In this work we develop a stochastic model of acute HIV infection, based on the well-known standard model, that allows us to simulate the complex mutation pathways of HIV escape from multiple CTL responses. Under this model, we describe two computational inference methods. In one, we use a Bayesian approach to construct posteriors for the parameters of
arxiv
Antibody-lectin chimeras for glyco-immune checkpoint blockade
bioRxivDespite the curative potential of checkpoint blockade immunotherapy, most patients remain unresponsive to existing treatments. Glyco-immune checkpoints – interactions of cell-surface glycans with lectin, or glycan-binding, immunoreceptors – have emerged ...
Jessica C. Stark +12 more
semanticscholar +1 more source
Superparamagnetic iron oxide nanoparticles conjugated with doxorubicin for targeting breast cancer [PDF]
arXiv, 2019 Development of the next generations of cancer therapy modalities is currently a crucial requirement of oncology. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are challenging the traditional distinction between diagnostic and treatment agents. The chase of innovative, multifunctional,
arxiv
Influence of non-specific immunologic factors on prognosis in advanced bronchogenic carcinoma
Cancer Immunology and Immunotherapy, 2004 A. Liberati +5 more
semanticscholar +1 more source