Results 51 to 60 of about 11,911 (226)
HLA, Vpu and ADCC correlates of a unique Chinese HIV-1 Positive village cohort
, 2018 The recent relative success of the Thai Vaccine trial and failure of the STEP trial have prompted renewed calls for a ‘back to basics’ approach. This premise dictates a greater and clearer understanding of the various immune parameters at play in HIV ...
Rai, Mohammad Ali
core +1 more source
Advanced Science, EarlyView.ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
, 2018 Corneal perforations are medical emergencies in which the cornea is partially or completely ruptured, resulting in the loss of stability of the whole eye.
Nizamoglu, Mehmet
core
The production of polyclonal, monoclonal and genetically-derived scFv antibody fragments for the detection of the ß-lactam antibiotic, cephalexin, in milk [PDF]
, 2006 This thesis describes the production of antibodies for the detection of cephalexin and their application in ELISA and Biacore ‘real-time’ surface plasmon resonance (SPR)-based biosensor assays.
Darmanin Sheehan, Alfredo
core
Advanced Science, EarlyView.AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li +6 more
wiley +1 more source
Indirect selective laser sintering of an apatite-mullite glass-ceramic [PDF]
, 2004 The main objective of this work was to determine the feasibility of using indirect selective laser sintering (SLS) to produce parts for bone replacement applications from glass-ceramic materials.
Goodridge, Ruth Davina
core
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source
Advanced Science, EarlyView.This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo +9 more
wiley +1 more source
PLGA-Nanopartikel für die inhalative Vakzinierung [PDF]
, 2014 Die vorliegende Arbeit umfasst die Entwicklung und Charakterisierung einer Vakzinformulierung für die pulmonale Applikation. Um dieses Ziel zu erreichen, wurden Nanopartikel aus dem Polymer PLGA hergestellt und mit dem Modellantigen Ovalbumin beladen ...
Janke, Julia
core
Advanced Science, EarlyView.Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao +12 more
wiley +1 more source