Results 61 to 70 of about 112,175 (268)

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Does Managerial Ability Improve Environmental Performance and Overall ESG Ratings? The Impact of the European Sustainability Reporting Mandate

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines the role of managerial ability in driving environmental performance and overall environmental, social, and governance (ESG) ratings in the context of the European Union sustainability reporting regulations. Using a sample of 7242 firm‐year observations over the period 2015–2023, our results indicate a structural change in ...
Mihaela Ionașcu   +2 more
wiley   +1 more source

Social Perception of Trees in the Landscape: The Connection Between Attitudes and Visual Preferences

open access: yesJournal of Landscape Ecology, 2023
The study presented in this paper uses a representative sample of the Czech population to analyse the relationships between attitudes to trees and preferences for landscapes with trees.
Stachová Jana, Čermák Daniel
doaj   +1 more source

The upper kHz QPO: a gravitationally lensed vertical oscillation

open access: yes, 2004
We show that a luminous torus in the Schwarzschild metric oscillating along its own axis gives rise to a periodically varying flux of radiation, even though the source of radiation is steady and perfectly axisymmetric.
Abramowicz M. A.   +5 more
core   +1 more source

Does Internal Corporate Social Responsibility Drive Employee Well‐Being? Evidence From a Positive Balance Perspective

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The significance of fostering an internal corporate social responsibility (ICSR) plan to advance employee well‐being is not fully understood. This article explores employee well‐being from a positive balance perspective, combining the strategic approach to Internal Corporate Social Responsibility with the Theory of subjective well‐being ...
Teresa C. Herrador‐Alcaide   +3 more
wiley   +1 more source

Populační vývoj Česka v roce 2023

open access: yesDemografie
The article describes demographic development in Czechia during 2023 and sets it in the context of the previous five years. It focuses on both population stock and the main demographic processes, namely fertility, mortality, nuptiality, the divorce rate,
Jana Koukalová
doaj   +1 more source

The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei

open access: yesDevelopmental Dynamics, EarlyView.
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Jeong Han Lee   +6 more
wiley   +1 more source

Demografické stárnutí v Česku mezi lety 2012–2022 prostřednictvím vybraných retrospektivních a prospektivních ukazatelů

open access: yesDemografie
Demographic ageing is considered a significant phenomenon and one of the most important population issues of the 21st century. It is a process that has no parallel in human history but is completely natural.
Filip Čábela, Luděk Šídlo
doaj   +1 more source

Theoretical and Methodological Aspects of the Identification and Delimitation of Peripheral Areas

open access: yesActa Universitatis Carolinae Geographica, 2016
This article focuses on the topic of the polarisation of space. Its objective is to give a basic overview of the theoretical and methodological aspects of research on peripheral areas and to discuss selected aspects.
Jan Pileček, Vít Jančák
doaj   +1 more source

Factors Influencing The Intention To Make Malaysia A Second Home: A Study On Japanese And Indonesian [PDF]

open access: yes, 2012
Tempat kediaman kedua atau skim pesaraan di luar negara merupakan konsep yang amat biasa di Eropah dan Amerika Utara.
Khu, Shin Yuin
core  

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