Results 1 to 10 of about 1,137 (172)

Application of the FDEM Based on the CZM in Simulating Three-Point Bending Test of Frozen Soil

Atmosphere, 2022
The combined finite–discrete element method (FDEM) based on the cohesive zone model (the CZM) achieves cracking simulation by inserting cohesive elements between solid elements.
Yongtao Wang
exaly   +3 more sources

Protective effects of biomimetic Cu-Zn-MOF against DOX-Induced cardiotoxicity through inhibiting oxidative stress and ferroptosis [PDF]

Journal of Nanobiotechnology
Background Doxorubicin (DOX), a member of the anthracycline family, is widely recognized as an effective chemotherapeutic agent for cancer treatment. However, its clinical application is limited due to its cardiotoxicity.
Jian Wang, Meng Zhao, Jian Zhang, Xiaoyan Zhang, Hongming Zhu, Changnan Wang, Song Zhang   +6 more
doaj   +2 more sources

Semi-analytical solution of cohesive zone model for cement-based materials [PDF]

Scientific Reports
The low tensile strength characteristics of cement-based materials are the biggest defect restricting their use. Understanding the mechanisms behind tensile cracking shows great significance in guiding the design of cement-based materials and their ...
Yong-Kang Hou, Shu-Jin Duan, Rui-Mei An, Xin-Yue Wang   +3 more
doaj   +2 more sources

Numerical Investigation of Asphalt Concrete Fracture Based on Heterogeneous Structure and Cohesive Zone Model [PDF]

Applied Sciences, 2022
The fracture behavior of asphalt concrete is closely related to its internal structure. A deep understanding of the relationship between the internal structure and fracture behavior of asphalt concrete is very important for sustainable and durable ...
Jiaqi Chen, Xu Ouyang, Xiao Sun
doaj   +2 more sources

Carfilzomib shows therapeutic potential for reduction of liver fibrosis by targeting hepatic stellate cell activation [PDF]

Scientific Reports
Because hepatic stellate cells (HSCs) play a major role in fibrosis, we focused on HSCs as a potential target for the treatment of liver fibrosis.
Ayana Fujiwara, Keisuke Takemura, Anna Tanaka, Misaki Matsumoto, Masato Katsuyama, Takeshi Okanoue, Kanji Yamaguchi, Yoshito Itoh, Kazumi Iwata, Kikuko Amagase, Atsushi Umemura   +10 more
doaj   +2 more sources

Simulation of microscopic fracture characteristics of fractured rock based on CZM-FDEM method. [PDF]

Sci Rep
Microstructural damage is an important cause of macrofracture in fissured rocks. To investigate the microscopic fracture mechanism of fissured rocks, a fissured rock model was established using the CZM-FDEM method. The model considers the mechanical behaviour of cohesive elements between particles within the rock and the propagation of cracks through ...
Zou Q, Li H, Zheng Y, Zhang X, Wang L, Zhang J.   +5 more
europepmc   +4 more sources

Penny-shaped cracks: A comparison between FFM and CZM

Procedia Structural Integrity, 2022
Pietro Cornetti, Alberto Sapora
exaly   +3 more sources

Study of influence of various loading parameters on crack propagation by using Cohesive Zone Modeling (CZM) approach

Open Engineering, 2012

exaly   +2 more sources

Study on the Degradation of SOFC Anodes Induced by Chemical and Electrochemical Sintering Using EIS and µ-CT

Applied Sciences, 2023
The goal of the present study was to quantify degradation phenomena on anodes that can be attributed to chemical (thermal) and/or electrochemical sintering, to find out the underlying mechanisms, and to propose countermeasures. The samples were thermally
Georgia Sourkouni, Christos Argirusis
doaj   +1 more source

Use of combined CZM and XFEM techniques for the patch shape performance analysis on the behavior of a 2024-T3 Aluminum structure reinforced with a composite patch

Fracture and Structural Integrity, 2022
The presence of a geometric discontinuity such as a crack or a notch can cause the failure of a structure during its use. Under various mechanical or thermal stresses, a high concentration of stresses can take place at the level of these discontinuities,
Safa Chahrazad Djebbar, Nadia Kaddouri, Mohamed ElAjrami, Mohamed Belhouari, Kouider Madani   +4 more
doaj   +1 more source