Results 101 to 110 of about 3,688,606 (250)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Mu Kara SaniLa vie communautaire dans les sociétés africaines tend à disparaître au moment où se développe l’individualisme. La communauté des Adja-Ewe de la préfecture de Yoto au Togo ne fait pas exception.
Hognon Kodjo, Napo Gbati
doaj
Les oasis de l'Oued Noun : dégradation du milieu naturel et perspectives de développement [PDF]
Cinq Continents, 2011 The oases of Oued Noun: degradation of the natural environment and perspectives of development. An oasis is considered as a vital space and a fundamental natural resource in the Oued Noun area.
EL MAHJOUB CHMOURK
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Utilisation des SIG pour l’évaluation de la qualité du couvert végétal dans le Haut Ouergha, Maroc
Revue Géomatique et Gestion des TerritoiresLe couvert végétal joue un rôle essentiel dans la protection des sols contre les divers processus de dégradation à travers la réduction de la vitesse du ruissellement sur les versants et l’atténuation de l’énergie cinétique des pluies.
Khadija EL OUAZANI ECH-CHAHDI +2 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Les facteurs de dégradation de l’espace oasien dans la province de Guelmim, Sud-Ouest Marocain [PDF]
Cinq Continents, 2019 Factors of degradation of the oases space in the province of Guelmim: South West marcoain. The province of Guelmim has thirteen oases. The city of Guelmim was originally an oasis before becoming a city received nomads and tribes from nearby areas and the
Hassan ATBIR
doaj
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source