Results 161 to 170 of about 768,215 (196)

Social determinants of mental health in Germany: a systematic scoping review mapping the landscape of researched determinants, outcome measures, and explanatory concepts. [PDF]

Int J Equity Health
Lehe MS, Reiß P, Jürgensen VC, Halbeisen G, Paslakis G.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Commercial determinants of health: an approach for strengthening One Health interventions. [PDF]

Front Public Health
Ebata A, Paichadze N, Abbas SS, Hyder AA, Bloom G.   +4 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Organ crosstalk and dysfunction in Sepsis: harnessing emerging biotechnologies for future breakthroughs

Annals of Intensive Care
Alexandre Pierre, Steve Lancel, Sebastien Preau   +2 more
doaj   +1 more source

School-age lung function after preterm birth: early-life determinants in a paediatric pulmonology cohort with comparison with NHANES. [PDF]

Thorax
Kelchtermans J, Rice JL, Aoyama BC, Collaco JM, McGrath-Morrow S.   +4 more
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Social determinants of health in medical education: insights from final-year students in a multicentre study in Italy. [PDF]

Updates Surg
Milanesi G, Khalil BA, Morabito A.
europepmc   +1 more source