Results 91 to 100 of about 83,781 (288)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Impact de l'évolution de la gestion des plantations de café sur la diversité des oiseaux cavicoles dans les Ghats Occidentaux, Inde [PDF]
, 2010 Cette étude est une tentative de rendre compte de l'état des systèmes agroforestiers à basé de café dans les Ghats Occidentaux (Inde) à travers les oiseaux cavicoles. Les plantations de café sont gérées selon un degré d'intervention humaine.
Torres, Ursula
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
L'évaluation du risque de récidive chez les agresseurs sexuels adultes [PDF]
, 2008 Mémoire numérisé par la Division de la gestion de documents et des archives de l'Université de ...
Parent, Geneviève
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Mu Kara SaniLa présente recherche vise à cerner les déterminants psychosociaux qui contribuent à la déviance chez les personnes souffrant de troubles mentaux. La démarche méthodologique adoptée prend en compte l’hôpital Psychiatrique de Bingerville comme terrain d ...
Kinanya Donatien Toure
doaj
SAGE Open, 2015 Extant empirical research has reported conflicting findings with respect to the effects of punishment certainty and punishment severity on organizational deviance, suggesting the need to introduce a moderator.
Kabiru Maitama Kura +2 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
, 2015 Ce travail traitera de l'enseignement de la déviance dans les cours de SES en Première. A la lumière d'une expérience d'enseignement de cette thématique et d'une enquête menée auprès d'enseignants titulaires, on cherchera ici à dresser un état des ...
Fileppo, Laurent
core