Results 101 to 110 of about 20,348,775 (251)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tailoring Intermediate Adsorption Through d‐band Mismatch Strategy of Heterojunction to Achieve Industrial Overall Water Splitting

open access: yesAdvanced Science
Adjusting the d‐band center of catalysts through heterojunction construction represents an effective approach for enhancing the catalytic activity. Nevertheless, the precise modulation pathways of d‐band centers still require systematic elucidation.
Jia Liu   +10 more
doaj   +1 more source

Coordination engineering directs d-band center optimization for efficient CO2 hydrogenation to formic acid on Ir–Nx single-atom catalysts

open access: yesAdvanced Powder Materials
The in-depth exploration of electronic structure serves as a cornerstone for rational catalyst design, which is essential to unlock the precise structure-activity relationships governing heterogeneous CO2 hydrogenation to formic acid. Herein, we report a
Yuankang Xu   +10 more
doaj   +1 more source

University Concert Band, October 8, 1992

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, October 8, 1992, 8:00 p.m., the 37th concert of the School of Music’s 1992-1993 season.University Concert Band, Stephen Grugin, conductor ...
Western Michigan University. Concert Band
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

University Symphonic Band, February 24, 1974

open access: yes, 2017
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 24, 1974, program no. 155 of the Department of Music’s 1973-1974 season.Western Michigan University Symphonic Band, Carl Bjerregaard ...
Western Michigan University. Symphonic Band
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Advanced electrocatalytic reforming of PET-derived ethylene glycol via electric field-driven d-band center modulation

open access: yesNano Research
The electrochemical upcycling of polyethylene terephthalate (PET) into high-value products, alongside hydrogen production under ambient conditions, represents a promising approach to sustainable waste management.
Jinyong Sun   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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