Results 111 to 120 of about 20,348,775 (251)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
University Symphonic Band, February 23, 1997
, 2016 Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 23, 1997, 3:00 p.m., the 349th concert of the School of Music's 1996-1997 season.Western Michigan University Symphonic Band, Robert L ...
Western Michigan University. Symphonic Band
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
University Symphonic Band, February 24, 1991
, 2016 Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 24, 1991, 3:00 p.m., the 253rd concert of the School of Music’s 1990-1991 season.University Symphonic Band, Richard J.
Western Michigan University. Symphonic Band
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2009 Black and white photo. Marichi band dressed in white costumes Santa Cecelia Band. Man holding clarinet second from left is Lorenzo Perea. Man sitting on center stool indentified as Adolfo Arizpe, original building owner of the Barelas Coffee ...
National Hispanc Cultural Center
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Dual-band electromagnetic band gap structure for noise isolation in mixed signal SiP
, 2010 A compact dual-band electromagnetic band-gap (EBG) structure is proposed. It is shown through numerical simulation using 3D full wave solver that by adding a slit to the classical mushroom shape an extra resonance is introduced and thus dual-band EBG ...
Rotaru, Mihai D., Sykulski, Jan K.
core +1 more source
Nature CommunicationsHigh-entropy alloys (HEAs) present a vast compositional space for fine-tuning electrocatalytic activities, leveraging millions of distinct active sites on the surface. However, the intricate local chemical environment poses challenges to the rational and
Guolin Cao +3 more
doaj +1 more source