, 1988 1984—1985年从武昌东湖定期采集形成水华的铜绿微囊藻Microcystisaeruginosa,并进行了毒素的分离与鉴定。结果表明:(1)用反复冻融的藻细胞糊对20—25g小白鼠进行腹腔注射,其最低致死浓度为100mg/kg(LD_(100)=100mg/kg),致死时间为60—120min。(2)用匀浆、抽提、离子交换层析及高压液相层析(HPLC)纯化了毒素,纯化毒素对小白鼠的最低致死量约为lmg/kg ...
何家菀,何振荣,俞家禄,俞敏娟
core
[Meige syndrome with dyspnea as main manifestation: a report of one case and literature review]. [PDF]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za ZhiLiu T, Xu J, Ye J.
europepmc +1 more source
, 1998 一种用于去除内毒素的亲和膜分离器，它是由底壳，壳底里表面形成的下压板，亲和膜介质，上压板，压环和上盖几个主要部分构成的，其中在底壳内加有带胶粘密封层的亲和膜介质，在亲和膜介质加上压板和在压板上装上压环，再将上盖用螺纹安装在底壳上，并使壳体内外密闭。该分离器可用于多种溶液，特别是水或生物样品溶液中内毒素的去除，溶液中的内毒素水平可降至０．１ｎｇ／ｍｌ以下，处理量可达几百毫升 ...
于亿年 +4 more
core
[Chinese expert consensus on chimeric antigen receptor T-cell therapy for multiple myeloma (2026)]. [PDF]
Zhonghua Xue Ye Xue Za ZhiChinese Medical Doctor Association +3 more
europepmc +1 more source
, 2009 微囊藻毒素（Microcystin，简称MC）是由淡水蓝藻产生的一种水溶性肝毒素。随着蓝藻水华在世界范围的淡水和咸水水体中的频繁发生，水华污染带来的水质安全问题和水产品安全问题已成为全球关注的卫生问题。微囊藻毒素标准品是开展为微囊藻毒素相关研究的必需的实验材料。为了解决我国对毒素标准品大量需求的矛盾，我们在借鉴了国内外已有经验的基础上，发展了微囊藻毒素的纯化新工艺。 以滇池天然水华蓝藻为原料，建立了以甲醇溶液、醋酸溶液提取，固相萃取和半制备色谱分离为主要步骤的微囊藻毒素分离纯化方法。通过优化提取 ...
余婷
core
[Research progress on toxic shock syndrome due to group A <i>Streptococcus</i> infection in children]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiWang HY, Zhou W, Huang LS.
europepmc +1 more source
[Comparison of antiviral efficacy of nucleos(t)ide analogue monotherapy and its combination with interferon-α in children 1-6 years-old with HBeAg-positive chronic hepatitis B]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWang ZW +11 more
europepmc +1 more source
[In vitro and in vivo antibacterial effects of the mitochondrial antioxidant Visomitin against <i>Enterococcus</i>]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanYang Q, Wu Y, Wu R, She P.
europepmc +1 more source
[Antibacterial activity and mechanism of the antiparasitic drug resorantel against <i>Staphylococcus epidermidis</i>]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanGuo S +6 more
europepmc +1 more source
[N-carbamylglutamate in the treatment of neonatal organic acidemia crisis: a report of five cases]. [PDF]
Zhongguo Dang Dai Er Ke Za ZhiZhao HY +5 more
europepmc +1 more source